中国强直性脊柱炎人群工作能力现状及影响因素分析  

Working ability of ankylosing spondylitis population in China and its influencing factors

作　　者：余晴 陈悦宁 刘宏潇[1] YU Qing;CHEN Yuening;LIU Hongxiao(Department of Rheumatology,Guang’anmen Hospital,China,Academy of Chinese Medical Sciences,Beijing 100053,China;Graduate School,Beijing University of Chinese Medicine,Beijing 100029,China)

机构地区：[1]中国中医科学院广安门医院风湿病科,北京100053 [2]北京中医药大学研究生院,北京100029

出　　处：《海军军医大学学报》2025年第4期488-496,共9页Academic Journal of Naval Medical University

基　　金：国家自然科学基金(81873292);北京市自然科学基金(7212190);中国中医科学院科技创新工程重大攻关项目(CI2021A01506)。

摘　　要：目的多中心、多层次、多维度探讨中国强直性脊柱炎(AS)患者工作能力现状,并分析AS患者工作能力状况的影响因素,为改善AS患者工作能力障碍结局提供帮助与借鉴。方法收集2022年3月至2023年9月就诊于中国9个中心10家医院的253例AS患者的人口学资料、工作能力及疾病相关信息,采用工作效率与活动影响调查问卷调查患者的工作情况,分析患者工作能力障碍的影响因素,并探讨工作能力与疾病严重程度、自我评估及心理状态等因素的相关性。结果共纳入253例AS患者,其中197例(77.87%)在职,76例(30.04%)工作状态正常,177例(69.96%)存在工作能力障碍。多因素logistic回归分析显示,AS病程、Bath强直性脊柱炎功能指数、Bath强直性脊柱炎测量指数、慢性病治疗功能评估-疲劳量表、包括红细胞沉降率的强直性脊柱炎疾病活动评分、国际脊柱关节炎协会健康指数、抑郁、焦虑、患者整体自我评价是影响患者工作能力的重要因素。结论中国AS患者工作能力障碍的发生率较高,疾病严重程度、心理状态和患者自我报告结局与工作能力现状密切相关。Objective To explore the status of working ability of patients with ankylosing spondylitis(AS)in China from multi-center,multi-level and multi-dimensional perspectives,and analyze the influencing factors of working ability in AS patients,so as to improve the outcome of working ability disorder in AS patients.Methods The demographic data,working ability and disease-related information of 253 AS patients admitted to 10 hospitals in 9 centers in China from Mar.2022 to Sep.2023 were collected.Work productivity and activity impairment questionnaire was used to investigate the working status.The influencing factors of working ability disorder were analyzed,and the correlations of the work ability with the severity of disease,self-assessment,and mental health status were discussed.Results A total of 253 patients with AS were enrolled,of which 197(77.87%)were employed,76(30.04%)were in normal working status,and 177(69.96%)had disorder in working ability.Multivariate logistic regression analysis showed that the course of AS,Bath ankylosing spondylitis functional index,Bath ankylosing spondylitis measurement index,functional assessment of chronic illness therapy-fatigue,ankylosing spondylitis disease activity score-erythrocyte sedimentation rate,Assessment of Spondyloarthritis International Society health index,depression,anxiety,and patient global assessment were important factors affecting the working ability of patients.Conclusion There is a high proportion of work ability disorder in Chinese AS patients,and the severity of the disease,psychological state and self-reported outcome are closely related to the status of work ability.

关 键 词：强直性脊柱炎 工作能力 工作效率与活动影响调查问卷 影响因素 

分 类 号：R593.23[医药卫生—内科学]