痰证临床疗效评价量表的研制  

The development of the clinical efficacy evaluation scale for phlegm syndrome

作　　者：吕行 刘文娜[1] 王建新 张瑜[1] 高蕊[2] LV Xing;LIU Wen-na;WANG Jian-xin;ZHANG Yu;GAO Rui(Dongfang Hospital Beijing University of Chinese Medicine,Beijing 100078,China;Xiyuan Hospital of China Academy of Traditional Chinese Medicine,Beijing 100091,China)

机构地区：[1]北京中医药大学第二临床学院,北京100078 [2]中国中医科学院西苑医院,北京100091

出　　处：《中国新药杂志》2025年第7期727-733,共7页Chinese Journal of New Drugs

基　　金：中国中医科学院科技创新工程资助项目(CI2021A04701)。

摘　　要：目的:基于定性定量相结合、主客观相结合、患者医生相结合构建痰证临床疗效评价指标,建立痰证临床疗效评价量表。方法:结合国内外量表科学的制定流程,采用混合研究方法中探索性序列的研究设计。通过文献研究、条目多轮筛选、专家电子问卷调查等定量研究方法,专家定性访谈及专家共识会议等定性研究方法对条目进行筛选、解释与优化。结果:痰证疗效评价量表共包含症状条目11个,其中局部症状6个,包括咯痰、痰质黏、痰鸣、脘痞、大便黏腻不爽、局部包块;全身症4个,包括肥胖、身体沉重、眩晕、头昏蒙;舌象条目1个,为苔腻。结论:本研究建立了量化有效、释义明确、操作简便的痰证疗效评价工具,为痰证疗效评价标准的研制和应用提供了有益的参考。Objective:To develop a clinical efficacy evaluation index of sputum syndrome that integrates indexes of qualitative and quantitative,subjective and objective,as well as patients and doctors,and to establish a comprehensive clinical efficacy evaluation scale for sputum pattern.Methods:Combined with the scientific formulation process of scales in China and abroad,the research design of exploratory sequences in mixed research methods was adopted.Quantitative research methods such as literature research,multi-round screening of items,and expert electronic questionnaire surveys,alongside qualitative research methods such as qualitative interviews with experts and expert consensus meetings were used to screen,interpret and optimize the items.Results:The sputum syndrome efficacy evaluation scale contained a total of 11 symptom items,including 6 local symptoms:phlegm,sputum stickiness,sputum sound,phlegm,sticky stool,and local mass;4 systemic symptoms:obesity,heaviness,dizziness,and dizziness,as well as 1 tongue image.Conclusion:This study has established a quantitative and effective tool for evaluating the efficacy of sputum syndrome,providing a useful reference for the development and application of the evaluation criteria for the efficacy of sputum syndrome.

关 键 词：中医证候研究 中医痰证 痰证疗效评价量表 混合研究方法 专家德尔菲法 

分 类 号：R95[医药卫生—药学]