专项处方点评模式对抗肿瘤药物合理使用的干预效果  

Intervention Effect of Special Prescription Comment Model on Rational Use of Anti-tumor Drugs

作　　者：杨军军 钱佳楠 梁锈瑛 郭小红[1] YANG Junjun;QIAN Jianan;LIANG Xiuying;GUO Xiaohong(Department of Pharmacy,Nantong Tumor Hospital,Nantong 226361,Jiangsu,China)

机构地区：[1]南通市肿瘤医院药学部,江苏南通226361

出　　处：《中国药物滥用防治杂志》2025年第2期236-238,共3页Chinese Journal of Drug Abuse Prevention and Treatment

基　　金：江苏省药学会-正大天晴医院药学科研基金项目(编号:Q202236)。

摘　　要：目的:观察专项处方点评模式对抗肿瘤药物使用的干预效果。方法:利用医院信息化系统,采用随机抽样方法,将2023年1月—12月选择在本院开具的2400份抗肿瘤药物处方作为对照组,2024年1月—12月选择在本院开具的2400份抗肿瘤药物处方作为点评组。对照组按照传统方法使用抗肿瘤药物,点评组按照专项处方点评模式使用抗肿瘤药物,比较两组处方不合理率、不良反应发生率及治疗总有效率。结果:点评组处方不合理率为1.00%,低于对照组的3.75%(P<0.05);点评组血液系统反应、消化系统反应、神经系统反应、过敏反应等不良反应发生率低于对照组(P<0.05);点评组总有效率为75.75%,高于对照组的63.00%(P<0.05)。结论:在抗肿瘤药物使用中应用专项处方点评模式能降低处方不合理率,也能降低不良反应发生率,促进治疗效果提高。Objective:To observe the intervention effect of special prescription review mode on the use of anti-tumor drugs.Methods:Using the hospital information system and random sampling method,2400 anti-tumor drug prescriptions issued in our hospital from January to December 2023 were selected as the control group,and 2400 anti-tumor drug prescriptions issued in our hospital from January to December 2024 were selected as the review group.The control group used anti-tumor drugs according to the traditional method,and the review group used anti-tumor drugs according to the special prescription review mode.The unreasonable rate of prescription,the incidence of adverse reactions and the total effective rate of treatment were compared between the two groups.Results:The unreasonable rate of prescription in the comment group was 1.00%,which was lower than 3.75%in the control group(P<0.05).The incidence of adverse reactions such as blood system reaction,digestive system reaction,nervous system reaction and allergic reaction in the observation group was lower than that in the control group(P<0.05).The total effective rate of the observation group was 75.75%,which was higher than 63.00%of the control group(P<0.05).Conclusion:The application of special prescription review mode in the use of anti-tumor drugs can reduce the unreasonable rate of prescriptions,reduce the incidence of adverse reactions,and promote the improvement of treatment effect.

关 键 词：专项处方点评模式 抗肿瘤药物 不合理处方 不良反应 治疗效果 

分 类 号：R95[医药卫生—药学]