经鼻高流量吸氧在慢性阻塞性肺疾病急性加重伴呼吸衰竭中的临床研究  

Clinical Study of Nasal High Flow Oxygen Therapy in Acute Exacerbation of Chronic Obstructive Pulmonary Disease with Respiratory Failure

作　　者：梁爱军[1] Liang Aijun(Department of Respiratory and Critical Care Medicine,Red Cross Hospital of Yulin City,Yulin,Guangxi 537000)

机构地区：[1]广西玉林市红十字会医院呼吸与危重症医学科,广西玉林537000

出　　处：《中外健康》2024年第8期80-82,共3页

摘　　要：探究对慢性阻塞性肺疾病急性加重期伴呼吸衰竭患者应用经鼻高流量吸氧的效果。选取广西玉林市红十字会医院呼吸与危重症医学科2022年1月1日―2023年4月30日期间慢性阻塞性肺疾病急性加重期伴呼吸衰竭患者60例为研究对象,随机分为参照组(n=30,常规氧疗)、试验组(n=30,经鼻高流量吸氧),对比两组临床疗效、血气分析指标、呼吸功能、氧合指数。研究结果显示,试验组临床疗效显著高于参照组(P<0.05);治疗后,试验组动脉氧分压、pH值显著高于参照组,动脉二氧化碳分压显著低于参照组(P<0.05);治疗后,试验组心率与呼吸频率显著低于参照组(P<0.05);治疗后,试验组氧合指数显著高于参照组(P<0.05)。研究发现,经鼻高流量吸氧在慢性阻塞性肺疾病急性加重期伴呼吸衰竭患者中的应用效果显著,具有较高的应用价值。To explore the effect of nasal high flow oxygen therapy on patients with acute exacerbation of chronic obstructive pulmonary disease accompanied by respiratory failure.Sixty patients with acute exacerbation of chronic obstructive pulmonary disease accompanied by respiratory failure at the Respiratory and Critical Care Medicine Department of Red Cross Hospital of Yulin City from January 1,2022 to April 30,2023 were selected as the study subjects.They were randomly divided into a reference group(=30,conventional oxygen therapy)and an experimental group(=30,nasal high flow oxygen therapy)to compare the clinical efficacy,blood gas analysis indicators,respiratory function,and oxygenation index between the two groups.The research results showed that the clinical efficacy of the experimental group was significantly higher than that of the reference group(<0.05).After treatment,the arterial oxygen partial pressure and pH value of the experimental group were significantly higher than those of the reference group,and the arterial carbon dioxide partial pressure was significantly lower than that of the reference group(<0.05).The heart rate and respiratory rate of the experimental group were significantly lower than those of the reference group(<0.05),and the oxygenation index of the experimental group was significantly higher than that of the reference group(<0.05).Research has found that nasal high flow oxygen therapy has significant application value in patients with acute exacerbation of chronic obstructive pulmonary disease accompanied by respiratory failure.

关 键 词：慢性阻塞性肺疾病 急性加重期 呼吸衰竭 经鼻高流量吸氧 疗效 

分 类 号：R563.9[医药卫生—呼吸系统]