从“郁”探析2型糖尿病发病规律  

Pathogenesis of Type 2 Diabetes Mellitus from Perspective of"Yu"

作　　者：王孟龙[1] 王彤瑞 谷峰[1] WANG Menglong;WANG Tongrui;GU Feng(Liaoning University of Traditional Chinese Medicine,Shenyang Liaoning China 110032;The Second Hospital Affiliated to Liaoning University of Traditional Chinese Medicine,Shenyang Liaoning China 110034)

机构地区：[1]辽宁中医药大学,辽宁沈阳110032 [2]辽宁中医药大学附属第二医院,辽宁沈阳110034

出　　处：《中医学报》2025年第4期778-782,共5页Acta Chinese Medicine

基　　金：国家中医药管理局第四批优秀人才(中医基础类)研修项目(10010244B10038)。

摘　　要：“郁”病机出处为《黄帝内经》,广义是指郁滞不通。临证基于“亢则害、承乃制”的五行思想谈人体五脏的生理性规律,通过论述承制关系维持人体血糖的稳定,引出“郁”病机为破坏人体“亢害承制”稳态的媒介。在“郁”的作用下,人体稳态发生变化,五脏的“亢害承制”关系出现问题,进而出现血糖异常。2型糖尿病则由脾土之郁发展为五脏之郁,郁火灼烧,终发消渴,病情日久变化,五脏虚损,毒郁内伤,损伤血脉,因而变生他证,故探求2型糖尿病的发病规律为:2型糖尿病不同阶段均可出现“郁结”的病机,是影响2型糖尿病发病以及发展的一个重要因素。The pathogenesis term of"Yu"was first proposed in Huang Di Nei Jing.In a broad sense,it refers to stagnation and blockage.Based on the Five Elements theory,"hyperactivity is harmful while balancing is stable",the physiological laws of the Five Zang of the human body is discussed.As to human′s blood glucose,it is also the case,namely,"Yu"pathogenesis injures the homeostasis of human body,which in turn leads to abnormal blood glucose.Type 2 diabetes mellitus,however,develops from the Yu of the Spleen to the depression of the Five Zang.When the Fire induced by Yu burns it leads to the development of Xiao Ke.When the condition progress over time,the Five Zang′s deficiency and Toxin injures the blood and meridians internally,resulting in other syndromes.Therefore,the pathogenesis of type 2 diabetes mellitus is explored as follows:the Yu pathogenesis of type 2 diabetes mellitus can be seen in different stages,and it is an important factor affecting the onset of type 2 diabetes mellitus as well as the development of the disease.

关 键 词：2型糖尿病 亢害承制 郁 脾瘅 消瘅 消渴 “毒郁” 

分 类 号：R259.871[医药卫生—中西医结合]