喜炎平注射液联合头孢克洛治疗小儿急性细菌性肠炎的临床效果  

Clinical Effect of Xiyanping Injection Combined with Cefaclor in the Treatment of Acute Bacterial Enteritis in Children

作　　者：赖珊 陈洪梅 LAI Shan;CHEN Hongmei(Department of Pediatrics,Jinsha County Chinese Medicine Hospital,Bijie 551800,Guizhou,China)

机构地区：[1]金沙县中医医院儿科,贵州毕节551800

出　　处：《世界复合医学(中英文)》2025年第1期6-9,共4页World Journal of Complex Medicine

摘　　要：目的探讨喜炎平注射液联合头孢克洛对儿童急性细菌性肠炎的临床效果。方法选取2023年1月—2024年2月金沙县中医医院收治的124例急性细菌性肠炎患儿为研究对象,根据不同的治疗方法分为对照组和研究组,各62例。对照组进行头孢克洛治疗,研究组在对照组基础上联合喜炎平注射液治疗。比较两组临床疗效、炎症指标、血常规、粪便常规以及粪便隐血试验指标、不良反应发生率。结果研究组治疗总有效率为98.39%(61/62),高于对照组的87.10%(54/62),差异有统计学意义(χ^(2)=5.871,P<0.05)。治疗后,研究组C-反应蛋白、降钙素原、白细胞计数、中性粒细胞均低于对照组,差异均有统计学意义(P均<0.05)。研究组不良反应发生率低于对照组,差异有统计学意义(P<0.05)。两组粪便隐血试验、白细胞、红细胞治疗后阳性例数比较,差异均无统计学意义(P均>0.05)。结论喜炎平注射液联合头孢克洛的治疗方案能抑制急性细菌性肠炎患儿的炎症反应,提升临床疗效及治疗安全性。Objective To investigate the clinical effect of Xiyanping Injection combined with cefaclor on acute bacterial enteritis in children.Methods A total of 124 children with acute bacterial enteritis admitted to Jinsha County Chinese Medicine Hospital from January 2023 to February 2024 were selected as the research objects.According to different treatment methods,they were divided into control group and study group,with 62 cases in each group.The control group was treated with cefaclor,and the study group was treated with Xiyanping Injection on the basis of the control group.The clinical efficacy,inflammatory indicators,blood routine,fecal routine,fecal occult blood test indicators and incidence of adverse reactions were compared between the two groups.Results The total effective rate of treatment in the study group was 98.39%(61/62),which was higher than 87.10%(54/62)in the control group,and the difference was statistically significant(χ^(2)=5.871,P<0.05).After treatment,the C-reactive protein,procalcitonin,white blood cell count and neutrophilicgranulocyte in the study group were lower than those in the control group,and the differences were statistically significant(all P<0.05).The incidence of adverse reactions in the study group was lower than that in the control group,the difference was statistically significant(P<0.05).There were no significant differences in the number of positive cases of fecal occult blood test,white blood cells and red blood cells after treatment between the two groups(all P>0.05).Conclusion The treatment of Xiyanping Injection combined with cefaclor can inhibit the inflammatory response of children with acute bacterial enteritis and improve the clinical efficacy and safety of treatment.

关 键 词：喜炎平注射液 头孢克洛 小儿急性细菌性肠炎 炎症指标 

分 类 号：R725.6[医药卫生—儿科]