压力微导管血流储备分数联合紫杉醇药物球囊在经皮冠状动脉介入治疗中的应用效果  

Application Effect of Pressure Microcatheter Fractional Flow Reserve Combined with Paclitaxel Drug Balloon in Percutaneous Coronary Intervention

作　　者：张燕 梅立冬 耿爽 ZHANG Yan;MEI Lidong;GENG Shuang(Department of Intensive Care Medicine,Hongxinglong Hospital of Beidahuang Group,Shuangyashan 155811,Heilongjiang,China;Department of Cardiology,Hongxinglong Hospital of Beidahuang Group,Shuangyashan 155811,Heilongjiang,China)

机构地区：[1]北大荒集团红兴隆医院重症医学科,黑龙江双鸭山155811 [2]北大荒集团红兴隆医院心内科,黑龙江双鸭山155811

出　　处：《世界复合医学(中英文)》2025年第1期19-23,共5页World Journal of Complex Medicine

基　　金：黑龙江省卫生健康委科研立项(20230303010028)。

摘　　要：目的分析在冠状动脉粥样硬化性心脏病(简称冠心病)经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)中采取压力微导管血流储备分数(fractional flow reserve,FFR)联合紫杉醇药物球囊的应用效果。方法选取2022年5月—2024年7月北大荒集团红兴隆医院重症医学科收治的100例接受PCI的冠心病患者,按照治疗方法不同分为研究组、对照组,各50例。研究组应用压力微导管FFR联合紫杉醇药物球囊治疗,对照组采用常规治疗,对比两组手术相关指标、心功能、靶血管狭窄程度、靶血管直径、并发症发生率。结果研究组平均支架植入数量为(0.87±0.12)个、对比剂应用量为(182.24±1.51)mL、手术时间为(51.63±1.37)min,均少于对照组的(1.56±0.25)个、(258.27±1.45)mL、(65.61±1.42)min,差异均有统计学意义(t=17.594、256.805、50.099,P均<0.05)。治疗后,研究组左心室射血分数、靶血管直径均高于对照组,靶血管狭窄程度低于对照组,差异均有统计学意义(P均<0.05)。研究组并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论压力微导管FFR联合紫杉醇药物球囊应用在PCI治疗中可改善冠心病患者的临床指标,并预防并发症的发生。Objective To analyze the application effect of pressure microcatheter fractional flow reserve(FFR)combined with paclitaxel drug balloon in percutaneous coronary intervention(PCI)of coronary atherosclerotic heart disease.Methods From May 2022 to July 2024,a total of 100 patients with coronary atherosclerotic heart disease who underwent PCI in the Department of Intensive Care Medicine of Hongxinglong Hospital of Beidahuang Group were selected and divided into study group and control group according to different treatment methods,with 50 cases in each group.The study group was treated with pressure microcatheter FFR combined with paclitaxel drug balloon,and the control group was treated with conventional treatment.The operation related indexes,cardiac function,target vessel stenosis degree,target vessel diameter and complication rate were compared between two groups.Results The average number of stent implantation in the study group was 0.87±0.12,the amount of contrast agent was(182.24±1.51)mL,and the operation time was(51.63±1.37)min,which were less than 1.56±0.25,(258.27±1.45)mL,(65.61±1.42)min in the control group,the differences were statistically significant(t=17.594,256.805,50.099,all P<0.05).After treatment,the left ventricular ejection fraction and target vessel diameter of the study group were higher than those of the control group,and the degree of target vessel stenosis was lower than that of the control group,the differences were statistically significant(all P<0.05).The incidence of complications in the study group was lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion The application of pressure microcatheter FFR combined with paclitaxel drug balloon therapy in PCI treatment can improve the clinical indicators of coronary atherosclerotic heart disease patients and prevent the occurrence of complications.

关 键 词：压力微导管血流储备分数 紫杉醇药物球囊 冠状动脉粥样硬化性心脏病 

分 类 号：R45[医药卫生—治疗学]