产后乐结合卡贝缩宫素治疗产后出血的效果  

Effect of Chanhoule Combined with Carbetocin in the Treatment of Postpartum Hemorrhage

作　　者：路倩 施亚洁 LU Qian;SHI Yajie(Department of Obstetrics and Gynecology,Wujin Hospital of Traditional Chinese Medicine,Changzhou 213161,Jiangsu,China)

机构地区：[1]常州市武进中医医院妇产科,江苏常州213161

出　　处：《世界复合医学(中英文)》2025年第1期61-64,共4页World Journal of Complex Medicine

摘　　要：目的探讨产后乐结合卡贝缩宫素治疗产后出血(postpartum hemorrhage,PPH)的疗效。方法回顾性选取2020年6月—2023年6月常州市武进中医医院收治的80例PPH患者的临床资料,按照不同的治疗方式分为对照组和观察组,各40例。对照组采用卡贝缩宫素治疗,观察组在对照组基础上联合产后乐治疗。比较两组产后出血量、凝血功能、临床疗效及不良反应发生情况。结果与对照组相比,观察组产后2 h、24 h出血量更少,差异均有统计学意义(P均<0.05)。治疗后,与对照组相比,观察组凝血酶原时间、活化部分凝血活酶时间、D-二聚体水平均更低,抗凝血酶Ⅲ水平更高,差异均有统计学意义(P均<0.05)。观察组治疗总有效率为95.00%(38/40),高于对照组的80.00%(32/40),差异有统计学意义(χ^(2)=4.114,P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论PPH患者采用产后乐+卡贝缩宫素可减少产后出血量,改善凝血功能,且安全性较高。Objective To explore the therapeutic effect of postpartum hemorrhage(PPH)with the combination of Chanhoule and carbetocin.Methods Clinical data of 80 patients with PPH admitted to Wujin Hospital of Traditional Chinese Medicine of Changzhou City from June 2020 to June 2023 were retrospectively selected and divided into control group and observation group according to different treatment methods,with 40 cases in each group.The control group was treated with carbetocin,and the observation group was treated with Chanhoule on the basis of the control group.The amount of postpartum hemorrhage,coagulation function,clinical efficacy and adverse reactions were compared between the two groups.Results Compared with the control group,the blood loss at 2 hours and 24 hours postpartum in the observation group were less,and the differences were statistically significant(both P<0.05).After treatment,compared with control group,the prothrombin time,activated partial thrombin time and D-dimer levels in observation group were lower,and the antithrombinⅢlevel was higher,and the differences were statistically significant(all P<0.05).The total effective rate of treatment in the observation group was 95.00%(38/40),which was higher than 80.00%(32/40)in the control group,the difference was statistically significant(χ^(2)=4.114,P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion PPH patients with Chanhoule+carbetocin can reduce postpartum hemorrhage,improve coagulation function,and the application safety is good.

关 键 词：产后出血 产后乐 卡贝缩宫素 凝血功能 不良反应 

分 类 号：R714[医药卫生—妇产科学]