经皮脊柱内镜下髓核摘除术治疗单节段腰椎间盘突出症患者的有效性及安全性  

Efficacy and Safety of Percutaneous Spinal Endoscopic Discectomy in the Treatment of Patients with Single Segment Lumbar Disc Herniation

作　　者：梅耀 冯建旭 郑寒 MEI Yao;FENG Jianxu;ZHENG Han(Department of Orthopedics,the People's Hospital of Daozhen Autonomous County,Zunyi 563500,Guizhou,China)

机构地区：[1]道真仡佬族苗族自治县人民医院骨科,贵州遵义563500

出　　处：《世界复合医学(中英文)》2025年第1期131-135,共5页World Journal of Complex Medicine

摘　　要：目的分析针对单节段腰椎间盘突出症采用经皮脊柱内镜下髓核摘除术治疗的效果。方法根据不同手术方法将2022年4月—2024年4月在道真仡佬族苗族自治县人民医院接受治疗的102例单节段腰椎间盘突出症患者分为两组。对照组(51例)实施经椎间孔椎体间融合术,观察组(51例)实施经皮脊柱内镜下髓核摘除术。比较两组手术指标、术后并发症、氧化应激指标、影像学指标、腰椎功能。结果观察组术后并发症发生率[1.96%(1/51)]相比于对照组[13.73%(7/51)]更低,差异有统计学意义(χ^(2)=4.883,P<0.05)。与对照组相比,观察组术中出血量更低,手术时间更短,术中的活性氧、氧化物歧化酶水平更低,术后1个月的腰椎曲度、腰骨倾斜角、腰椎前凸角度均更高,术后1个月、3个月、6个月的腰椎功能评分更高,差异均有统计学意义(P均<0.05)。结论采用经皮脊柱内镜下髓核摘除术治疗单节段腰椎间盘突出症患者,可改善其腰椎功能和影像学指标,且安全性高。Objective To analyze the effect of percutaneous spinal endoscopic nucleus pulposus removal in the treatment of single-segment lumbar disc herniation.Methods According to different surgical methods,102 patients with single-segment lumbar disc herniation who were treated in the People's Hospital of Daozhen Autonomous County from April 2022 to April 2024 were divided into two groups.The control group(51 cases)underwent transforaminal lumbar interbody fusion surgery,and the observation group(51 cases)underwent percutaneous spinal endoscopic nucleus pulposus removal.The surgical indicators,postoperative complications,oxidative stress indicators,imaging indicators,and lumbar function were compared between the two groups.Results The incidence of postoperative complications in the observation group[1.96%(1/51)]was lower than that in the control group[13.73%(7/51)],and the difference was statistically significant(χ^(2)=4.883,P<0.05).Compared with the control group,the intraoperative blood loss in the observation group was lower and the operation time was shorter,the levels of reactive oxygen species and oxide dismutase during the operation were lower,the lumbar curvature,lumbar inclination angle and lumbar lordosis angle of one month after operationin were higher,the lumbar function score of one month,three months and six months after operation were higher,and the differences were statistically significant(all P<0.05).Conclusion The application of percutaneous spinal endoscopic nucleus pulposus removal can improve the lumbar function and imaging indexes of patients with single-segment lumbar disc herniation,and has high safety.

关 键 词：单节段腰椎间盘突出症 经皮脊柱内镜下髓核摘除术 有效性 安全性 

分 类 号：R68[医药卫生—骨科学]