健康体检者甲状腺结节的检出情况及危险因素分析  

Analysis of detection and risk factors of thyroid nodules in physical examination population

作　　者：努尔比亚·米尔扎木[1] 热孜耶姆·麦麦提 杨晓萍[1] Nuerbiya·MIERZAMU;Reziyemu·MAIMAITI;YANG Xiaoping(the First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,China)

机构地区：[1]新疆医科大学第一附属医院,新疆乌鲁木齐830054

出　　处：《临床医学研究与实践》2025年第10期18-21,共4页Clinical Research and Practice

基　　金：新疆维吾尔自治区自然科学基金资助项目(No.2024D01C183)。

摘　　要：目的分析健康体检人群甲状腺结节(TN)的检出情况及危险因素。方法选取2022年1月至12月在新疆医科大学第一附属医院健康管理中心完成健康体检的11136例体检者,分析TN的检出情况及其危险因素。结果11136例体检者中,TN检出率为55.00%;TN组与正常组的年龄、性别及身体质量指数(BMI)比较,差异具有统计学意义(P<0.05);TN组的血糖(GLU)、总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)水平高于正常组,而高密度脂蛋白胆固醇(HDL-C)水平低于正常组(P<0.05)。不同结节分级患者的年龄、性别、BMI占比比较,差异具有统计学意义(P<0.05)。多因素Logistic回归分析显示,年龄、性别、BMI及GLU、TC、TG、HDL-C是影响TN发生的因素(P<0.05)。结论新疆地区TN患病率较高,高龄、女性、超重/肥胖及糖脂代谢异常人群为高危群体,建议针对此类人群加强筛查并实施代谢健康管理。Objective To analysis the detection and risk factors of thyroid nodules(TN)in physical examination population.Methods A total of 11136 subjects who completed the physical examination in the health management center of the First Affiliated Hospital of Xinjiang Medical University from January to December 2022 were selected,and the detection and risk factors of TN were analyzed.Results Among the 11136 subjects,the detection rate of TN was 55.00%;there were significant differences in age,gender and body mass index(BMI)between TN group and normal group(P<0.05);the levels of glucose(GLU),total cholesterol(TC),triglyceride(TG)and low-density lipoprotein cholesterol(LDL-C)in the TN group were higher than those in the normal group,while the high-density lipoprotein cholesterol(HDL-C)level was significantly lower than that in the normal group(P<0.05).There were statistically significant differences in the proportion of age,gender and BMI among patients with different nodule grades(P<0.05).Multivariate Logistic regression analysis showed that age,gender,BMI,GLU,TC,TG and HDL-C were the influencing factors of TN(P<0.05).Conclusion The prevalence of TN in Xinjiang region is high,and advanced age,female,overweight/obesity and abnormal glucose and lipid metabolism are high-risk groups.It is recommended to strengthen screening and implement metabolic health management for such groups.

关 键 词：健康体检 甲状腺结节 新疆地区 

分 类 号：R581[医药卫生—内分泌]