专项行动和综合考核干预对提高住院患者抗菌药物使用前病原学送检率的效果分析  

Analysis of the effect of special action and comprehensive assessment intervention on improving the rate of etiological examination before the use of antibiotics in hospitalized patients

作　　者：李明 李金红 陈兴文 LI Ming;LI Jinhong;CHEN Xingwen(Department of Infection Control Office/Prevention and Protection,the Nuclear Industry 417 Hospital,Xi'an,Shaanxi 710600,China)

机构地区：[1]核工业四一七医院感染办/防保科,陕西西安710600

出　　处：《医药前沿》2025年第11期138-140,143,共4页Journal of Frontiers of Medicine

基　　金：国家卫生健康委医院管理研究所“提高住院患者抗菌药物治疗前病原送检率”专项行动(国卫医研函[2021]198号);核工业四一七医院科研预研基金项目(HGY417-QN-2024-19)。

摘　　要：目的分析专项行动和综合考核干预对提高住院患者抗菌药物使用前病原学送检率的效果。方法选取2023年1—9月核工业四一七医院的住院患者共23617例为研究对象。2023年1—6月未实施专项行动和综合考核干预,即干预前,共纳入13339例住院患者;2023年7—9月已实施专项行动和综合考核干预,即干预后,共纳入10278例住院患者。收集并比较干预前后住院患者抗菌药物使用前病原学送检情况、不同科室住院患者抗菌药物使用前病原学送检情况和限制级抗菌药物使用前病原学送检情况。结果干预前住院患者治疗性抗菌药物使用率为27.84%,干预后为18.31%;干预前住院患者治疗性抗菌药物使用前病原学送检率为42.95%,干预后为75.19%,干预后住院患者治疗性抗菌药物使用前病原学送检率高于干预前,差异有统计学意义(P<0.05)。干预前住院患者限制级抗菌药物使用率为8.08%,干预后为9.88%;干预前住院患者限制级抗菌药物使用前病原学送检率为46.66%,干预后为81.58%,干预后住院患者限制级抗菌药物使用前病原学送检率高于干预前,差异有统计学意义(P<0.05)。干预前后重症监护室、内科、外科、妇科和综合科住院患者治疗性抗菌药物使用前病原学送检率比较,差异无统计学意义(P>0.05)。结论专项行动和综合考核干预可以提高住院患者治疗性抗菌药物使用前病原学送检率和限制级抗菌药物使用前病原学送检率,从而规范临床抗菌药物的合理使用。Objective To analyze the effect of special action and comprehensive assessment intervention on improving the rate of pathogenic examination before the use of antibiotics in hospitalized patients.Methods A total of 23617 hospitalized patients from January to September 2023 in the Nuclear Industry 417 Hospital were selected as the research objects.From January to June 2023,no special action and comprehensive assessment intervention were implemented,which is before the intervention,a total of 13339 hospitalized patients were included;from July to September 2023,special actions and comprehensive assessment interventions have been implemented,which is after the intervention,a total of 10278 inpatients were included.To collect and compare the pathogenic submission before the use of antibiotics in hospitalized patients before and after the intervention,the pathogenic submission before the use of antibiotics in hospitalized patients in different departments and the pathogenic submission before the use of restricted antibiotics.Results The utilization rate of therapeutic antibiotics in hospitalized patients before intervention was 27.84%,and that after intervention was 18.31%.The rate of pathogenic examination before the use of therapeutic antibiotics in hospitalized patients was 42.95%before the intervention and 75.19%after the intervention.The rate of pathogenic examination before the use of therapeutic antibiotics in hospitalized patients after the intervention was higher than that before the intervention,and the difference was statistically significant(P<0.05).The use rate of restricted antibiotics in hospitalized patients before intervention was 8.08%,and 9.88%after intervention.Before the intervention,the pathogenic submission rate of hospitalized patients before the use of restricted antibiotics was 46.66%,and after the intervention was 81.58%.After the intervention,the pathogenic submission rate of hospitalized patients before the use of restricted antibiotics was higher than that before the intervention,and the d

关 键 词：专项行动和综合考核干预 住院患者 抗菌药物 病原学 送检率 

分 类 号：R91[医药卫生—药学]