有创-无创序贯通气联合肠内营养支持治疗ICU危重呼吸衰竭患者的效果  

Effect of Invasive-noninvasive Sequential Ventilation Combined with Enteral Nutrition Support in ICU Patients with Critical Respiratory Failure

作　　者：梁拯铭 邱顺年 LIANG Zhengming;QIU Shunnian(Department of Critical Care Medicine,Jiangle General Hospital,Jiangle,Fujian,353300,China)

机构地区：[1]将乐县总医院重症医学科,福建将乐353300

出　　处：《中外医疗》2025年第7期21-25,共5页China & Foreign Medical Treatment

摘　　要：目的探究有创-无创序贯通气与肠内营养支持在重症加强监护病房(intensive care unit,ICU)危重呼吸衰竭患者中联合应用的临床效果。方法方便选取2021年3月—2024年1月将乐县总医院收治的137例危重呼吸衰竭患者为研究对象,根据不同治疗方案分为两组,对照组(68例)接受有创通气、肠内营养支持联合方案治疗。研究组(69例)在肠内营养支持的基础上,实施有创-无创序贯通气治疗。比较两组患者临床治疗有效率、并发症发生率、临床指标、血气指标水平、营养指标水平和炎症因子水平。结果与对照组的治疗总有效率83.82%(57/68)比较,观察组的95.65%(66/69)更高,差异有统计学意义(χ^(2)=5.223,P=0.022)。研究组并发症总发生率低于对照组,总通气时间、入住ICU时间、住院总时间均短于对照组,差异均有统计学意义(P均<0.05)。治疗5 d后,研究组动脉血氧分压、血氧饱和度、pH、血清白蛋白、前白蛋白水平均高于对照组,动脉血二氧化碳分压、降钙素原、C反应蛋白、白细胞介素-6水平均低于对照组,差异均有统计学意义(P均<0.05)。结论ICU危重呼吸衰竭患者治疗中采取有创-无创序贯通气,联合肠内营养支持治疗,可以缩短总通气时间、入住ICU时间、住院总时间,维持患者生命体征平稳,提高营养水平,减轻炎症反应。Objective To explore the clinical effect of combined use of invasive-noninvasive ventilation and enteral nutrition support in patients with critical respiratory failure in intensive care unit(ICU).Methods A total of 137 patients with critical respiratory failure admitted to Jiangle General Hospital from March 2021 to January 2024 were conveniently selected as the study subjects and divided into two groups according to different treatment plans.The control group(68 cases)received invasive ventilation and enteral nutrition support combined treatment.The study group(69 cases)received invasive-noninvasive ventilation therapy on the basis of enteral nutrition support.The effective rate of clinical treatment,complication rate,clinical indexes,blood gas indexes,nutritional indexes and inflammatory factors were compared between the two groups.Results Compared with the total effective rate of 83.82%(57/68)in the control group,95.65%(66/69)in the observation group was higher,and the difference was statistically significant(χ^(2)=5.223,P=0.022).The total incidence of complications in the study group was lower than that in the control group,and the total ventilation time,ICU stay time and total hospitalization time were shorter than those in the control group,the differences were statistically significant(all P<0.05).After 5 days of treatment,the levels of arterial partial pressure of oxygen,blood oxygen saturation,pH,serum albumin and prealbumin in the study group were higher than those in the control group,and the levels of arterial partial pressure of carbon dioxide,procalcitonin,C-reactive protein and interleukin-6 were lower than those in the control group,the differences were statistically significant(all P<0.05).Conclusion In the treatment of ICU patients with critical respiratory failure,the combination of invasive-noninvasive sequential ventilation and enteral nutrition support can shorten the total ventilation time,stay in ICU,and hospitalization time,maintain the stable vital signs of patients,improve the level o

关 键 词：重症加强监护病房 呼吸衰竭 有创-无创序贯通气 肠内营养支持 

分 类 号：R563.8[医药卫生—呼吸系统]