痰热互结型冠状动脉粥样硬化性心脏病伴焦虑患者采用小陷胸汤合温胆汤加减治疗的效果  

Clinical Effect of the Treatment of Patients with Coronary Heart Disease of Phlegm-heat Syndrome with Anxiety by Modified Xiaoxianxiong Decoction Combined with Wendan Decoction

作　　者：金军 JIN Jun(Longjing Hospital of Traditional Chinese Medicine,Longjing,Jilin,133400,China)

机构地区：[1]吉林省龙井市中医医院,吉林龙井133400

出　　处：《中外医疗》2025年第8期130-133,共4页China & Foreign Medical Treatment

摘　　要：目的探讨痰热互结型冠状动脉粥样硬化性心脏病(简称冠心病)伴焦虑患者采用小陷胸汤合温胆汤加减治疗的临床效果。方法回顾性选取2022年4月—2024年2月吉林省龙井市中医医院收治的120例痰热互结型冠心病伴焦虑患者的临床资料,以不同治疗方法分组,其中对照组60例接受心可舒片治疗,联合组60例加用小陷胸汤合温胆汤加减治疗。对比两组患者的负性情绪、中医证候积分、氧化应激水平和不良反应发生情况。结果治疗后,联合组负性情绪评分、中医证候积分低于对照组,差异均有统计学意义(P均<0.05)。治疗后,联合组氧化应激水平优于对照组,差异有统计学意义(P<0.05)。联合组不良反应总发生率为6.67%(4/60),低于对照组的20.00%(12/60),差异有统计学意义(χ^(2)=4.615,P<0.05)。结论针对痰热互结型冠心病并伴有焦虑症状患者采用小陷胸汤联合温胆汤的加减疗法,相较于单独使用心可舒片,在改善患者情绪、减轻临床症状以及缓解氧化应激反应方面效果更佳,并且能够降低不良反应的发生率。Objective To explore the clinical effect of modified Xiaoxianxiong decoction combined with Wendan decoction in the treatment of coronary heart disease of phlegm-heat syndrome with anxiety.Methods The clinical data of 120 patients with coronary heart disease of phlegm-heat type with anxiety admitted to Longjing Hospital of Traditional Chinese Medicine of Jilin Province from April 2022 to February 2024 were retrospectively selected and divided into groups with different treatment methods,60 cases in each group.The control group was treated with Xinkeshu tablets,and the combined group was add with modified Xiaoxianxiong decoction and Wendan decoction.The negative emotions,traditional Chinese medicine syndrome scores,oxidative stress levels and adverse reactions were compared between the two groups.Results After treatment,the negative emotion score and traditional Chinese medicine syndrome scores of the combined group were lower than those of the control group,and the differences were statistically significant(both P<0.05).The level of oxidative stress in the combined group was better than that in the control group,and the difference was statistically significant(P<0.05).The total incidence of adverse reactions in the combined group was 6.67%(4/60),which was lower than 20.00%(12/60)in the control group,and the difference was statistically significant(χ^(2)=4.615,P<0.05).Conclusion The modified Xiaoxianxiong decoction and Wendan decoction was used to treat patients with coronary heart disease of phlegm-heat type with anxiety,compared with Xinkeshu tablets alone,it was more effective in improving patients'emotional status,reducing clinical symptoms and alleviating oxidative stress reaction,and could reduce the incidence of adverse reactions.

关 键 词：痰热互结型冠心病 焦虑 小陷胸汤 温胆汤 临床效果 

分 类 号：R256[医药卫生—中医内科学]