两种胰岛素用药方式治疗急诊糖尿病酮症酸中毒的血糖水平影响分析  

Influence of Two Insulin Medication Methods on Blood Glucose Level in Emergency Diabetic Ketoacidosis

作　　者：江小昱 李百来 阙茂棋 JIANG Xiaoyu;LI Bailai;QUE Maoqi(Department of Emergency,Xiamen Fifth Hospital,Xiamen 361101,Fujian,China)

机构地区：[1]厦门市第五医院急诊科,福建厦门361101

出　　处：《糖尿病新世界》2025年第5期5-7,23,共4页Diabetes New World

摘　　要：目的探讨比较两种胰岛素用药方式治疗急诊糖尿病酮症酸中毒血糖水平的影响。方法选取2022年9月—2024年9月厦门市第五医院急诊科就诊治疗的70例急诊糖尿病酮症酸中毒患者,依据不同用药方式进行分组,观察组(35例)接受微量泵持续皮下注射胰岛素,对照组(35例)均予以持续静脉输注胰岛素,对比两组治疗效果、血糖水平、临床指标。结果治疗后,与对照组相比,观察组空腹血糖水平更低,胰岛素用量、血糖达标时间、血酮体和尿酮体恢复时间均更优,低血糖发生率更低,差异均有统计学意义(P均<0.05)。观察组治疗总有效率略高于对照组,但差异无统计学意义(P>0.05)。结论微量泵持续皮下输注胰岛素在急诊糖尿病酮症酸中毒治疗中对血糖水平的调控效果更佳,可作为优选方案,但需根据患者具体情况综合考虑用药方式。Objective To explore and compare the effects of two insulin medication methods on blood glucose levels in the treatment of emergency diabetic ketoacidosis.Methods A total of 70 patients with emergency diabetic ketoacidosis who were treated in Department of Emergency of Xiamen Fifth Hospital from September 2022 to September 2024 were selected and grouped according to different medication methods.The observation group(35 cases)received continuous subcutaneous injection of insulin by micropump,and the control group(35 cases)received continuous intravenous infusion of insulin.The therapeutic effect,blood glucose levels and clinical indicators between two groups were compared.Results After treatment,compared with the control group,the level of fasting blood glucose in the observation group was lower,the insulin dosage,the time of blood glucose reaching the standard,the recovery time of blood ketone body and urine ketone body were better and the incidence of hypoglycemia was lower,the differences were statistically significant(all P<0.05).The total effective rate of the observation group was slightly higher than that of the control group,but the difference was not statistically significant(P>0.05).Conclusion Continuous subcutaneous insulin infusion with micropump has a better effect on the regulation of blood glucose level in the treatment of emergency diabetic ketoacidosis,which can be used as a preferred scheme,but it is necessary to comprehensively consider the medication method according to the specific conditions of the patients.

关 键 词：急诊糖尿病酮症酸中毒 治疗效果 血糖水平 

分 类 号：R587.2[医药卫生—内分泌]