研究超敏C-反应蛋白、血脂、血糖检验在糖尿病新发患者检验中的作用  

Study of the Role of High-sensitive C-reactive Protein,Blood Lipid and Blood Glucose Tests in the Testing of New-onset Diabetic Patients

作　　者：韩乃丽 韩向民 HAN Naili;HAN Xiangmin(Department of Laboratory Medicine,Jinan Zhangqiu District Hospital of TCM,Jinan 250200,Shandong,China)

机构地区：[1]济南市章丘区中医医院检验科,山东济南250200

出　　处：《糖尿病新世界》2025年第5期35-38,共4页Diabetes New World

摘　　要：目的探讨临床对糖尿病新发患者给予超敏C-反应蛋白(high-sensitive C-reactive protein,hs-CRP)+血脂+血糖检验的应用价值。方法选取2020年5月—2024年5月济南市章丘区中医医院收治的60例疑似糖尿病新发患者,临床对所有疑似糖尿病新发患者合理展开hs-CRP+血糖诊断、血脂+血糖诊断以及三项联合诊断,将口服葡萄糖耐量试验结果作为诊断金标准,对上述各种诊断方案的诊断效能实施对比。结果血脂+血糖检验对疑似糖尿病新发患者的阳性检出率为35.00%(21/60),阴性检出率为65.00%(39/60);hs-CRP+血糖检验的阳性检出率为31.67%(19/60),阴性检出率为68.33%(41/60);三项联合检验的阳性检出率为38.33%(23/60),阴性检出率为61.67%(37/60)。三项联合检验灵敏度、准确度均高于血脂+血糖、hs-CRP+血糖检验,差异均有统计学意义(P均<0.05)。结论临床对糖尿病新发患者在开展诊断工作期间,hs-CRP、血脂、血糖检验三项联合诊断可将各自的诊断优势充分结合,进一步提升糖尿病的诊断效能,为早期诊治提供依据。Objective To explore the clinical application value of high-sensitive C-reactive protein(hs-CRP)+blood lipid+blood glucose test in new-onset diabetic patients.Methods From May 2020 to May 2024,60 patients with suspected new-onset diabetes admitted to Jinan Zhangqiu District Hospital of TCM were selected.Clinically,hs-CRP+blood glucose diagnosis,blood lipid+blood glucose diagnosis and three combined diagnosis were reasonably carried out for all patients with suspected new-onset diabetes.Oral glucose tolerance test result was used as the gold standard for diagnosis,and the diagnostic efficacy of the above various diagnostic schemes was compared.Results The positive detection rate of blood lipid+blood glucose test for suspected new-onset patients with diabetes was 35.00%(21/60),and the negative detection rate was 65.00%(39/60).The positive detection rate of hs-CRP+blood glucose test was 31.67%(19/60),and the negative detection rate was 68.33%(41/60).The positive detection rate of the three combined tests was 38.33%(23/60),and the negative detection rate was 61.67%(37/60).The sensitivity and accuracy of the three combined tests were higher than those of blood lipid+blood glucose and hs-CRP+blood glucose tests,and the differences were statistically significant(both P<0.05).Conclusion During the clinical diagnosis of new patients with diabetes,the combined diagnosis of hs-CRP,blood lipid and blood glucose test can fully combine their respective diagnostic advantages,further improve the diagnostic efficiency of diabetes,and provide a basis for early diagnosis and treatment.

关 键 词：超敏C-反应蛋白 血脂 血糖检验 糖尿病新发 诊断效能 

分 类 号：R587.1[医药卫生—内分泌] R446.11[医药卫生—内科学]