分析血糖指标在糖尿病检验中的应用价值  

Application Value of Blood Glucose Index in Diabetes Mellitus Test

作　　者：房丽娜[1] 刘艳[1] 李健美[1] FANG Lina;LIU Yan;LI Jianmei(Department of Clinical Laboratory,Zibo Maternal and Child Health Hospital,Zibo 255000,Shandong,China)

机构地区：[1]淄博市妇幼保健院检验科,山东淄博255000

出　　处：《糖尿病新世界》2025年第5期39-42,共4页Diabetes New World

摘　　要：目的探究糖尿病检验中血糖及血脂指标的应用价值。方法选取2023年9月—2024年9月淄博市妇幼保健院收治的80例糖尿病患者为研究组,同期选取80例健康者为对照组。按照胰岛素抵抗程度将研究组患者分为轻度组(n=30,空腹胰岛素25~<200 pmol/L)、中度组(n=30,空腹胰岛素200~1000 pmol/L)、重度组(n=20,空腹胰岛素>1000 pmol/L)。比较组间血糖及血脂指标水平,并分析血糖、血脂指标与胰岛素抵抗程度的相关性。结果研究组空腹血糖(fasting plasma glucose,FPG)、餐后2 h血糖(2-hour postprandial plasma glucose,2 hPG)、糖化血红蛋白(glycated hemoglobin A1c,HbA1c)、总胆固醇(total cholesterol,TC)、甘油三酯(triglyceride,TG)、低密度脂蛋白胆固醇(low density lipoprotein cholesterol,LDL-C)水平均高于对照组,高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-C)水平低于对照组,差异均有统计学意义(P均<0.05)。轻度组、中度组、重度组FPG、2 hPG、HbA1c、TC、TG、HDL-C、LDL-C水平比较,差异均有统计学意义(P均<0.05)。相关性分析结果显示,FPG、2 hPG、HbA1c、TC、TG、LDL-C水平与胰岛素抵抗严重程度呈正相关,HDL-C水平与胰岛素抵抗严重程度呈负相关。结论血糖指标的筛查价值较高,可提高糖尿病筛查质量,辅以血脂检测能更好地分析患者的代谢情况与胰岛素抵抗程度,适用于糖尿病的诊断。Objective To explore the application value of blood glucose and blood lipid indexes in diabetes mellitus test.Methods A total of 80 patients with diabetes mellitus admitted to Zibo Maternal and Child Health Hospital from September 2023 to September 2024 were selected as the study group,and 80 healthy people were selected as the control group.According to the degree of insulin resistance,the patients in the study group were divided into mild group(n=30,fasting insulin 25-<200 pmol/L),moderate group(n=30,fasting insulin 200-1000 pmol/L)and severe group(n=20,fasting insulin>1000 pmol/L).The levels of blood glucose and blood lipid indexes were compared between groups,and the correlation between blood glucose,blood lipid indexes and insulin resistance was analyzed.Results The levels of fasting plasma glucose(FPG),2-hour postprandial plasma glucose(2 hPG),glycated hemoglobin A1c(HbA1c),total cholesterol(TC),triglyceride(TG)and low density lipoprotein cholesterol(LDL-C)in the study group were higher than those in the control group,the level of high density lipoprotein cholesterol(HDL-C)was lower than that of the control group,and the differences were statistically significant(all P<0.05).There were statistically significant differences in FPG,2 hPG,HbA1c,TC,TG,HDL-C and LDL-C levels among mild group,moderate group and severe group(all P<0.05).Correlation analysis showed that FPG,2 hPG,HbA1c,TC,TG,and LDL-C levels were positively correlated with the severity of insulin resistance,and HDL-C levels were negatively correlated with the severity of insulin resistance.Conclusion The screening value of blood glucose index is high,which can improve the quality of diabetes mellitus screening.Combined with blood lipid detection,it can better analyze the metabolism and insulin resistance of patients,which is suitable for the diagnosis of diabetes mellitus.

关 键 词：血糖指标 血脂指标 糖尿病 

分 类 号：R587.1[医药卫生—内分泌]