七氟醚联合瑞芬太尼在妇科腹腔镜手术麻醉中的效果观察  

Observation of the Effect of Sevoflurane Combined with Remifentanil in Gynecological Laparoscopic Surgery Anesthesia

作　　者：刘文超 LIU Wenchao(Department of Anesthesiology,Chaoyang Second Hospital,Chaoyang,Liaoning 122000,China)

机构地区：[1]朝阳市第二医院麻醉科,辽宁朝阳122000

出　　处：《中国医药指南》2025年第11期98-101,共4页Guide of China Medicine

摘　　要：目的研究将七氟醚联合瑞芬太尼应用在妇科腹腔镜手术麻醉中所发挥的麻醉作用。方法选取2024年1月—9月于朝阳市第二医院接受治疗的117例妇科腹腔镜手术患者,根据麻醉方法不同分为观察组(60例)和对照组(57例)。对照组麻醉中采用丙泊酚联合瑞芬太尼,观察组麻醉中使用七氟醚联合瑞芬太尼,对比两组患者的麻醉恢复指标、不同时间段的血流动力学指标、麻醉深度适宜度、不良反应发生率。结果观察组的各项麻醉恢复指标都比对照组更短(P<0.05)。T0时两组的心率和平均动脉压比较,差异无统计学意义(P>0.05);T1、T2时,观察组心率和平均动脉压比对照组更高(P<0.05)。观察组的麻醉深度适宜度比对照组更好(P<0.05)。观察组的麻醉不良反应总发生率对照组更低(P<0.05)。结论将七氟醚联合瑞芬太尼应用在妇科腹腔镜手术麻醉中有助于促进患者术后的麻醉指标的恢复,稳定患者的血流动力学,维持恰当的麻醉深度,且不会产生严重的不良反应,有助于手术的顺利开展和术后的快速恢复。Objective To examine the efficacy of remifentanil when used in conjunction with sevoflurane for anesthesia in gynecological laparoscopic surgeries.Methods A total of 117 patients scheduled for gynecological laparoscopic procedures at Chaoyang Second Hospital between January 2024 and September 2024.Participants were systematically allocated into two cohorts:60 cases in the intervention arm and 57 cases in the comparator arm,differentiated by anesthetic protocols.The comparator arm received conventional intravenous anesthesia with propofol-remifentanil combination,whereas the intervention arm underwent inhalation anesthesia using sevoflurane supplemented with remifentanil.Comparative analyses were conducted across four dimensions:postanesthesia recovery profiles,longitudinal hemodynamic stability measurements at predefined intervals,maintenance of optimal anesthetic depth throughout procedures,and occurrence rates of perioperative adverse events.Results The intervention cohort demonstrated significantly reduced postanesthetic recovery durations compared to the comparator group(P<0.05),with clinical relevance observed in emergence timeline metrics.At baseline(T0),no intergroup disparities were identified in either heart rate variability or mean arterial pressure(both P>0.05).During surgical stimulation phases(T1)and extubation period(T2),the intervention group exhibited elevated cardiovascular responsiveness,with significantly higher heart rate and mean arterial pressure readings than the comparator cohort(P<0.05).The intervention arm showed superior consistency in achieving target bispectral index(BIS)ranges,indicating more precise depth control compared to the comparator group(P<0.05).A significantly lower incidence of perioperative adverse events,including emergence agitation and respiratory depression,was documented in the intervention cohort(P<0.05).Conclusions The application of sevoflurane combined with remifentanil in gynecological laparoscopic surgery anesthesia can help promote the recovery of postoperativ

关 键 词：七氟醚 瑞芬太尼 妇科 腹腔镜 麻醉深度 血流动力学 

分 类 号：R614[医药卫生—麻醉学] R713[医药卫生—外科学]