新疆高龄老年人血红蛋白分布特征及参考值范围  

Distribution characteristics and reference range of hemoglobin in the elderly in Xinjiang

作　　者：杨星雨 王红梅[2] Yang Xingyu;Wang Hongmei(School of Medicine,Shihezi University,Shihezi 832003,Xinjiang Uygur Autonomous Region,China;Comprehensive Health Department,People's Hospital of Xinjiang Uygur Autonomous Region,Urumqi 830001,China)

机构地区：[1]石河子大学医学院,新疆石河子832003 [2]新疆维吾尔自治区人民医院综合保健内科,乌鲁木齐830001

出　　处：《中华老年多器官疾病杂志》2025年第3期217-221,共5页Chinese Journal of Multiple Organ Diseases in the Elderly

摘　　要：目的探讨新疆高龄老年人血红蛋白(Hb)的分布特征及参考值范围。方法采用简单随机抽样法在新疆开展横断面研究,自2019年1月至12月,在调查点随机招募≥80岁健康高龄老年人完成问卷调查和血样采集。采用百分位数法确定Hb的参考范围,分析Hb的年龄、性别、海拔、地区分布特征。采用SPSS 26.0统计软件进行数据分析。利用箱式图去除Hb数据中的离群值,采用K-S检验对Hb数据进行正态性检验。Hb参考值范围采用百分位数法确定(P 2.5,P 97.5)。结果本研究共招募≥80岁常住居民14554名,最终纳入13073例进行数据分析。新疆高龄男性Hb参考区间为108.0~173.0 g/L,高龄女性Hb参考区间为103.1~160.0 g/L,参考值下限均低于我国成年人水平,且参考值范围较宽。新疆高龄老年人Hb分布特征为男性高于女性(143.0和132.0 g/L;P<0.001),80~90岁年龄段高于≥90岁年龄段(P<0.001),高海拔地区高于低海拔地区(P<0.001),南疆高于北疆和东疆(P<0.001)。结论本研究首次建立了新疆地区≥80岁老人Hb的参考区间,新疆高龄老年人Hb存在性别、海拔、年龄、地区差异。Objective To investigate the distribution characteristics and reference range of hemoglobin(Hb)in the elderly in Xinjiang.Methods A cross-sectional study was conducted in Xinjiang using simple random sampling.From January to December 2019,healthy elderly individuals aged≥80 years were randomly recruited at survey sites to participate in a questionnaire survey and provide blood samples.The reference range of hemoglobin was established using the percentile method,and the age,gender,altitude,and regional distribution characteristics of Hb were analyzed.SPSS 26.0 was used for statistical analysis.Box plots were used to remove outliers in the Hb data,and the Kolmogorov Smirnov test(K-S test)was used for normality verification of Hb data.The range of Hb reference range was determined using the percentile method(P 2.5,P 97.5).Results A total of 14554 permanent residents aged≥80 years were recruited in this study,with 13073 included in the data analysis.The Hb reference range was 108.0-173.0 g/L for elderly males and 103.1-160.0 g/L elderly females in Xinjiang,showing both lower limits of the reference values lower than that for Chinese adults and a wide reference range itself.The distribution of hemoglobin among elderly people in Xinjiang was characterized by a higher value in males than in females(143.0 vs 132.0g/L;P<0.001),a higher value in the 80-90 years age group than the≥90 years age group(P<0.001),higher Hb levels in the high-altitude areas than in the low-altitude areas(P<0.001),and higher Hb levels in the southern Xinjiang than in the northern and eastern Xinjiang(P<0.001).Conclusion This study is the first to establish a Hb reference range in the elderly aged≥80 years in Xinjiang,revealing significant differences in gender,altitude,age,and region in hemoglobin levels among this population.

关 键 词：新疆 高龄 血红蛋白 参考区间 

分 类 号：R552[医药卫生—血液循环系统疾病]