间质性肺疾病患者发生静脉血栓栓塞的相关影响因素分析  

Analysis of related influencing factor of venous thromboembolism in patients with interstitial pulmonary disease

作　　者：邢琳琳[1] 高志国[1] 吴红芝 宋龙霞 王楠 张仕东[2] Xing Linlin;Gao Zhiguo;Wu Hongzhi;Song Longxia;Wang Nan;Zhang Shidong(Department of Respiratory and Critical Care Medicine,Xingtai People's Hospital,Xingtai 054000,Hebei,China;Department of Vascular Surgery,Xingtai People's Hospital,Xingtai 054000,Hebei,China)

机构地区：[1]邢台市人民医院呼吸与危重症医学一科,河北邢台054000 [2]邢台市人民医院血管外科,河北邢台054000

出　　处：《血管与腔内血管外科杂志》2025年第2期261-265,共5页Journal of Vascular and Endovascular Surgery

摘　　要：目的探讨间质性肺疾病(ILD)患者发生静脉血栓栓塞(VTE)的相关影响因素。方法收集2021年1月至2023年12月邢台市人民医院收治的116例ILD患者的临床资料,按照是否发生VTE将其分为VTE组(n=25)和对照组(n=91)。收集两组患者的临床相关指标,分析ILD患者发生VTE的影响因素。结果VTE组患者年龄、吸烟比例、合并肺动脉高压比例均高于对照组患者,服用阿司匹林比例低于对照组患者,差异均有统计学意义(P﹤0.05)。多因素分析结果显示,老年(≥60岁)、吸烟、合并肺动脉高压以及服用阿司匹林均是ILD患者发生VTE的危险因素(P﹤0.05)。所有VTE患者均接受相应的治疗,除1例大面积PE患者经过抢救无效死亡外,其他患者均恢复良好。结论ILD患者发生VTE风险较高,老年(≥60岁)、吸烟、合并肺动脉高压以及服用阿司匹林均是ILD患者发生VTE的独立危险因素,临床上应据此及时发现高危人群,积极给予相应的治疗。Objective To investigate the related factors of venous thromboembolism(VTE)in patients with interstitial lung disease(ILD).Method Clinical data of 116 ILD patients admitted to Xingtai People's Hospital from January 2021 to December 2023 were collected and divided into VTE group(n=25)and control group(n=91)according to whether VTE occurred.The clinical indicators of the two groups were collected and the influencing factors of VTE in ILD patients were analyzed.Result The patients in VTE group were higher than those in control group in age,smoking proportion and pulmonary arterial hypertension proportion,and the proportion of taking aspirin was lower than that in control group,with statistical significance(P<0.05).Multivariate analysis showed that old age(≥60 years old),smoking,pulmonary hypertension and aspirin were the risk factors for VTE in ILD patients(P<0.05).All VTE patients received corresponding treatment,except for one large-area PE patient who died after rescue,the other patients recovered well.Conclusion Old age(≥60 years old),smoking,pulmonary hypertension and aspirin use are independent risk factors for VTE in ILD patients.Therefore,high risk groups should be identified in time and appropriate treatment should be given.

关 键 词：间质性肺疾病 静脉血栓栓塞 影响因素 

分 类 号：R543[医药卫生—心血管疾病]