慢性心力衰竭患者与其流体智力的相关性研究  

Study on the Relationship Between Fluid Intelligence and Chronic Heart Failure

作　　者：刘佳月 冯玉宝[2] LIU Jiayue;FENG Yubao(Ordos Central Hospital Inner Mongolia Autonomous Region inten sive care unit,Erdos 017000 China;Ordos Central Hospital Inner Mongolia Autonomous Region,Internal Medicine-Cardiovascular Department,Erdos 017000 China)

机构地区：[1]鄂尔多斯市中心医院重症医学科,内蒙古鄂尔多斯017000 [2]鄂尔多斯市中心医院心内科,内蒙古鄂尔多斯017000

出　　处：《内蒙古医学杂志》2025年第2期129-135,139,共8页Inner Mongolia Medical Journal

摘　　要：目的探讨慢性心力衰竭(CHF)患者与其流体智力(FI)的相关性。方法选取2020年10月至2021年10月于鄂尔多斯市中心医院心内科就诊的112例患者,将其中符合纳入标准的77例CHF患者分为实验组,35例非CHF患者分为对照组。对比两组一般资料及瑞文标准推理测验(SPM)评分;根据左室射血分数(LVEF)不同分为射血分数降低的心衰(HFrEF)、射血分数保留的心衰(HFpEF)和射血分数轻度降低的心衰(HFmrEF),比较不同LVEF患者SPM评分;并分析CHF患者LVEF、前体脑钠肽(NT-proBNP)与SPM的关系。结果对照组和实验组在左房内径(LAd)、左心室舒张末期内径(LVEDd)、LVEF、NT-proBNP方面差异具有统计学意义(P<0.05);对照组和实验组在性别、年龄、是否吸烟、是否饮酒、是否合并高血压、是否合并糖尿病、舒张末期左室后壁厚度(LVPWd)、总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、脂蛋白a[Lp(a)]等方面差异无统计学意义(P>0.05)。CHF患者的“知觉辨别”“类同比较”“推理能力”“系列关系”“抽象推理”评分及总分均降低(P<0.05)。可以认为HFpEF患者的LVEDd与另外两组患者的LVEDd不同,HFpEF患者的LVED d最短(P<0.05);HFrEF患者与HFpEF患者的NT-proBNP不同,HFrEF患者的NT-pro BNP较高(P<0.05)。与另外两组患者相比,HFrEF患者的“知觉辨别”“类同比较”“推理能力”“系列关系”评分和SPM总分最低(P<0.05)。SPM评分与LVEF呈正相关(r=0.732,P<0.001),SPM评分与NT-proBNP呈负相关(r=-0.335,P=0.003)。不同受教育程度的CHF患者SPM单项得分及总分差异无统计学意义(P均>0.05)。LVEF的增加降低了CHF患者FI水平受损的风险,差异具有统计学意义(OR=0.703,95%CI 0.570~0.867,P=0.001)。结论CHF患者SPM总分及各单项得分均降低,且SPM评分与LVEF呈正相关,与NT-proBNP呈负相关,不同受教育程度的CH F患者的SPM单项得分及总分差异无统计�Objective To investigate if there is a fluid intelligence change in patients with Chronic Heart Failure(CHF)or not.Methods A total of 112 patients in the Department of Cardiology of Ordos Central Hospital from October 2020 to October 2021 were selected.Among them,77 patients with CHF who met the inclusion criteria were selected as the experimental group.The other 35 patients without CHF were selected as the control group,while the other 35 patients without CHF were selected as the control.The general information and Raven`s Standard Progressive Matrices(SPM)scores of the two groups were compared.According to different left ventricular ejection fraction(LVEF),the patients were divided into heart failure with reduced ejection fraction(HFrEF),heart failure with preserved ejection fraction(HFpEF),and heart failure with mildly reduced ejection fraction(HFmrEF).The SPM scores of patients with different LVEF were compared.The relationship between LVEF,NT-proBNP and SPM in patients with CHF was analyzed,and the relationship between SPM and LVEF,NT-proBNP and SPM was analyzed.Results There was a statistically significant difference in the cardiac function grade of control group and experimental group with LAd、LVED LVEF NT-proBNP(P<0.05).There was no significant difference between the control group and the experimental group in gender,age,smoking,drinking or hypertension,LVPWd,TC/TG/LDL-C/HDL-C/Lp(α)(P>0.05).The scores and total scores of“perception discrimination”“analogy comparison”“reasoning ability”“series relationship”and“abstract reasoning”in CHF patients were decreased(P<0.05).It can be considered that LVed in HFpEF patients is different from that in the other two groups.The LVed of patients with HFpEF was the shortest(P<0.05).It can be considered that NT-proBNP in HFrEF patients is different from that in HFpEF patients.The levels of NT-proBNP in patients with HFrEF were higher than those in patients with HFrEF(P<0.05).Compared with the other two groups of patients.The scores of“perception d

关 键 词：慢性心力衰竭 流体智力 瑞文标准推理测验 

分 类 号：R541.7[医药卫生—心血管疾病]