幼儿着色性干皮病继发下唇鳞癌1例  

A case of squamous cell carcinoma of the lower lip secondary to xeroderma pigmentosum in a child

作　　者：李世勇 吴勇[1,2] 张馨 马文 王思航[1,2] 付帅 LI Shiyong;WU Yong;ZHANG Xin;MA Wen;WANG Sihang;FU Shuai(Department of Oral and Maxillofacial Surgery,Stomatology Hospital of Kunming Medical University,Kunming 650106,China)

机构地区：[1]昆明医科大学附属口腔医院口腔颌面外科,云南昆明650106 [2]云南省口腔医学重点实验室,云南昆明650106 [3]云南师范大学校医院口腔科,云南昆明650500

出　　处：《口腔医学》2025年第3期210-212,共3页Stomatology

基　　金：云南省科技厅-昆医联合专项(202201AY070001-176)。

摘　　要：着色性干皮病(xeroderma pigmentosum,XP)是一种罕见的常染色体隐性遗传疾病,与XP基因的变异有关,常继发恶性肿瘤。该文对1例着色性干皮病继发下唇鳞癌的幼儿病例进行报道,并通过相关文献复习,对着色性干皮病的临床特点、发生机制、临床病理表现及预后进行讨论。Xeroderma pigmentosum(XP)is a rare autosomal recessive disorder related to XP gene variation,often causing secondary malignant tumors.This article reports a case of a young child with secondary squamous cell carcinoma of the lower lip caused by xeroderma pigmentosum.Through a review of relevant literature,the clinical characteristics,pathogenesis,clinical pathological manifestations,and prognosis of XP are discussed.

关 键 词：着色性干皮病 鳞癌 颌面部 

分 类 号：R758.58[医药卫生—皮肤病学与性病学]