苯海拉明联合己酮可可碱治疗急性眩晕的临床疗效分析  

Clinical Efficacy Analysis of Diphenhydramine Combined with Pentoxifylline in the Treatment of Acute Dizziness

作　　者：张志江 吕汶彩 欧阳升[1] ZHANG Zhijiang;LYU Wencai;OUYANG Sheng(Department of Neurology,First People's Hospital of Baiyin,Baiyin 730900,Gansu,China)

机构地区：[1]甘肃省白银市第一人民医院神经内科,甘肃白银730900

出　　处：《系统医学》2025年第3期85-87,91,共4页Systems Medicine

摘　　要：目的探讨急性眩晕使用盐酸苯海拉明注射液联合己酮可可碱治疗的临床价值。方法非随机选取2022年1月—2023年12月甘肃省白银市第一人民医院神经内科收治的78例急性眩晕症患者为研究对象,按照治疗方法不同分为两组,每组39例。对照组患者采用己酮可可碱治疗,观察组患者采用盐酸苯海拉明注射液联合己酮可可碱治疗。比较两组患者眩晕改善时间、住院天数、眩晕程度评分、治疗效果以及不良反应。结果观察组眩晕改善时间、住院天数、眩晕程度优于对照组,差异有统计学意义(P均<0.05)。在总有效率方面,对照组为79.49%(31/39),低于观察组的94.87%(37/39),差异有统计学意义(χ^(2)=4.129,P<0.05)。两组不良反应总发生率比较,差异无统计学意义(P>0.05)。结论盐酸苯海拉明注射液联合己酮可可碱治疗急性眩晕症效果显著,可有效改善患者眩晕。Objective To explore the clinical value of diphenhydramine hydrochloride injection combined with pentoxifylline in the treatment of acute dizziness.Methods A total of seventy-eight patients with acute vertigo admitted to the Department of Neurology of the First People's Hospital of Baiyin City,Gansu Province from January 2022 to December 2023 were non-randomly selected as the research objects.They were divided into two groups according to different treatment methods,with thirty-nine patients each.The control group was treated with pentoxifylline,while the observation group was treated with diphenhydramine hydrochloride injection combined with pentoxifylline.Compare the improvement time of dizziness,length of hospital stay,dizziness degree score,therapeutic outcome,and adverse reactions between two groups of patients.Results In terms of length of stay,dizziness improvement time,dizziness degree,the observation group were better than those in the control group,and the differences were statistically significant(all P<0.05).In terms of total efficiency,the observation group was 94.87%(37/39),higher than 79.49%(31/39)in the control group,and the difference was statistically significant(χ^(2)=4.129,P<0.05).There was no statistical significant difference in the total incidence of adverse reactions between the two groups.Conclusion The combination of diphenhydramine hydrochloride injection and pentoxifylline has a significant therapeutic effect on acute dizziness,which can effectively improve dizziness in patients.

关 键 词：苯海拉明 己酮可可碱 联合治疗 急性眩晕 临床疗效 

分 类 号：R4[医药卫生—临床医学]