ALB、TC、AST、ALT在肝硬化诊断中的应用  

Application of ALB,TC,AST and ALT in the diagnosis of Liver Cirrhosis

作　　者：李朋 程珊 李佳琪 LI Peng;CHENG Shan;LI Jiaqi(Wenshang County People′s Hospital,Jining 272500,Shandong,China)

机构地区：[1]汶上县人民医院,山东济宁272500

出　　处：《系统医学》2025年第6期51-53,共3页Systems Medicine

摘　　要：目的探讨分析天冬氨酸氨基转移酶(aspartate aminotransferase,AST)、谷丙转氨酶(alanine aminotransfer-ase,ALT),白蛋白(albumin,ALB)、总胆固醇(total cholesterol,TC)在肝硬化诊断中的应用价值。方法非随机选取2020年1月—2022年12月汶上县人民医院收治的60例肝硬化患者作为研究组,并选取同期体检健康志愿者50名作为对照组。对比两组ALB、TC、AST、ALT检验结果,分析研究组肝功能不同分级患者ALB、TC、AST、ALT检验结果。结果研究组ALB(25.46±3.02)g/L、TC(2.33±0.38)mmol/L,低于对照组的(57.46±5.63)g/L、(4.86±0.95)mmol/L,研究组AST(96.22±5.46)U/L、ALT(56.82±5.46)U/L,高于对照组的(15.22±1.21)U/L、(9.25±1.03)U/L,差异有统计学意义(t=18.562、13.568、20.458、22.715,P均<0.05)。研究组中肝功能不同分级患者ALB、TC、AST、ALT水平对比,差异有统计学意义(P均<0.05)。结论对肝硬化患者采取ALB、TC、AST、ALT四项检验,可提高诊断准确性。Objective To explore the value of analysing aspartate aminotransferase(AST),alanine aminotransferase(ALT),albumin(AlB),total cholesterol(TC)in the diagnosis of liver cirrhosis.Methods Sixty patients with liver cir-rhosis admitted to Wenshang County People's Hospital from January 2020 to December 2022 were non-randomly se-lected as the study group,and fifty healthy volunteers with medical checkup at the same time selected as the control group.Compared the ALB,TC,AST and ALT test results of the two groups,and analyzed the ALB,TC,AST and ALT test results of patients with different grade sof liver function in the study group.Results The ALB(25.46±3.02)g/L and TC(2.33±0.38)mmol/L in the study group were lower than(57.46±5.63)g/L and(4.86±0.95)mmol/L in the con-trol group,and the AST(96.22±5.46)U/L and ALT(56.82±5.46)U/L in the study group were higher than(15.22±1.21)U/L and(9.25±1.03)U/L in the control group,and the differences were statistically significant(t=18.562,13.568,20.458,22.715,all P<0.05).There was statistically significant difference in the comparison of ALB,TC,AST,and ALT levels of patients with different grades of liver function in the study group(all P<0.05).Conclusion Adopting the four tests of ALB,TC,AST and ALT in cirrhotic patients can improve the diagnostic accuracy.

关 键 词：肝硬化 指标检验 肝功能CHILD-PUGH分级 应用价值 

分 类 号：R466.11[医药卫生—临床医学]