剖宫产术后皮下注射低分子肝素预防静脉血栓形成的效果分析  

Prevention of Venous Thrombosis by Subcutaneous Injection of Low Mo⁃lecular Weight Heparin after Cesarean Section

作　　者：曾凡丽 黄淑静 杨堉梅 ZENG Fanli;HUANG Shujing;YANG Yumei(Department of Obstetrics and Gynecology,Jingping County People′s Hospital,Qiandongnan Prefecture 556700,Guizhou,China)

机构地区：[1]锦屏县人民医院妇产科,贵州黔东南州556700

出　　处：《系统医学》2025年第6期161-164,共4页Systems Medicine

摘　　要：目的针对接受剖宫产手术的患者,术后给予皮下注射低分子肝素,观察预防静脉血栓的效果。方法目的选取2022年10月—2023年10月锦屏县人民医院妇产科收治的200例剖宫产术后患者为研究对象。根据治疗方法不同分为两组,对照组(n=98)采用常规方式治疗,观察组(n=102)在对照组基础上增加低分子肝素治疗。就两组术后出血量、术后下床时间、住院时间、凝血功能、静脉血栓发生率展开对比。结果两组患者术后情况比较,观察组住院时间(6.28±1.33)d短于对照组的(9.78±2.24)d,差异有统计学意义(t=13.498,P<0.05)。两组术后出血量、术后下床活动时间比较,差异无统计学意义(P均>0.05)。治疗后,观察组纤维蛋白原(4.01±0.51)g/L低于对照组的(4.99±0.93)g/L,凝血酶原时间(13.67±2.33)s、活化部分凝血酶时间(32.61±3.12)s长于对照组的(12.55±1.89)s、(28.82±3.07)s,差异有统计学意义(t=9.289、3.725、8.655,P均<0.05)。观察组静脉血栓发生率为4.90%(5/102),比对照组的13.27%(13/98)低,差异有统计学意义(χ^(2)=4.269,P<0.05)。结论剖宫产术后皮下注射低分子肝素,可预防静脉血栓,促进产妇康复。Objective To observe the effect of subcutaneous injection of low molecular weight heparin on preventing venous thrombosis in patients after cesarean section.Methods 200 patients who underwent cesarean section and were admitted to the Department of Obstetrics and Gynecology of Jinping County People's Hospital from October 2022 to October 2023 were purpose selected as the research subjects.They were divided into two groups according to different treatment methods.The control group(n=98)received conventional treatment,and the observation group(n=102)re-ceived low molecular weight heparin treatment on the basis of the control group.Postoperative blood loss,postopera-tive time of getting out of bed,hospital stay,coagulation function and incidence of venous thrombosis were compared between the two groups.Results The hospitalization time of the observation group(6.28±1.33)d was shorter than that of the control group(9.78±2.24)d,and the difference was statistically significant(t=13.498,P<0.05).After treatment,fibrinogen(4.01±0.51)g/L in the observation group was lower than that in the control group(4.99±0.93)g/L,prothrom-bin time(13.67±2.33)s,activated partial thrombin time(32.61±3.12)s was longer than those in the control group(12.55±1.89)s,(28.82±3.07)s,the differences were statistically significant(t=9.289,3.725,8.655,all P<0.05).Con-clusion Subcutaneous injection of low-molecular-weight heparin after cesarean section is beneficial for preventing ve-nous thrombosis,promote maternal rehabilitation.

关 键 词：剖宫产 低分子肝素 静脉血栓 凝血功能 下床时间 住院时间 

分 类 号：R714[医药卫生—妇产科学]