阴道微生态菌群与宫颈人乳头瘤病毒感染的相关性研究进展  

Research progress on the relationship between vaginal microbiota and cervical HPV infection

作　　者：刘彦伯 金鑫 凌心茹 冯冠男[1] LIU Yanbo;JIN Xin;LING Xinru;FENG Guannan(Department of Obstetrics and Gynaecology,Suzhou Municipal Hospital,Suzhou,Jiangsu 215001,China)

机构地区：[1]南京医科大学附属苏州医院妇产科,江苏苏州215001

出　　处：《安徽医药》2025年第5期869-874,共6页Anhui Medical and Pharmaceutical Journal

基　　金：苏州市科技发展计划(SYS2020175);苏州市临床重点病种诊疗技术专项(LCZX202013);南京医科大学姑苏学院科研项目(GSKY20210203)。

摘　　要：女性的生殖道由阴道、子宫、输卵管和卵巢组成,具有较为独特的微生态构造,生活在其中的微生物菌群数量占女性细菌总数的9%,在防御病原体侵袭女性生殖道的方面有着举足轻重的作用。其中,女性阴道的微生态菌群构与对子宫颈人乳头瘤病毒(HPV)持续感染有着一定的相关性。现就女性阴道微生物菌群的主要构成、不同有益菌群作用机制与HPV侵袭感染子宫颈之间的相关性研究进展进行文献综述。The female reproductive tract comprises the vagina,uterus,fallopian tubes,and ovaries,and has a unique micro-ecological structure.The microflora accounts for 9%of the total number of bacteria in women and plays a crucial role in defending against pathogens that attack the female reproductive tract.The composition of the vaginal microflora is correlated with the persistence of cervical infection by human papillomavirus.This literature review examines the correlation between the main components of the female vaginal microflora and the mechanisms of action of different beneficial flora in relation to HPV infection of the uterine cervix.

关 键 词：微生物群落 阴道 人乳头瘤病毒 女性生殖道 微生态制剂 

分 类 号：R711.3[医药卫生—妇产科学]