基于ROC曲线评估NLR、BNP、hs-CRP联合检测在老年患者肺部感染预后中的价值  

To Evaluate the Value of Combined Detection of NLR,BNP and hs-CRP in the Prognosis of Pulmonary Infection in Elderly Patients Based on ROC Curve

作　　者：詹友斌 ZHAN Youbin(Department of Respiratory Medicine,Second People's Hospital of Lai'an County,Anhui Province,Chuzhou 239236,Anhui,China)

机构地区：[1]安徽省来安县第二人民医院呼吸内科,安徽滁州239236

出　　处：《系统医学》2025年第4期91-94,共4页Systems Medicine

摘　　要：目的研究中性粒细胞与淋巴细胞比值(neutrophil and lymphocyte ratio,NLR)、血B型脑钠肽(blood type B brain natriuretic peptide,BNP)与超敏C反应蛋白(hypersensitive C-reactive protein,hs-CRP)在评估老年社区获得性肺炎患者预后中的作用。方法回顾性选取2023年1—12月来安县第二人民医院收治的91例老年社区获得性肺炎患者的临床资料,根据患者预后和出院随访情况将其分为良好组(n=44)与一般组(n=47)。通过单因素及多因素Logistic回归分析判定影响老年社区获得性肺炎患者预后的独立危险因素,绘制ROC曲线分析AUC、敏感度和特异度。结果经单因素分析显示,良好组患者NLR、BNP、hs-CRP水平均低于一般组,住院天数少于一般组,差异有统计学意义(P均<0.05)。经多因素Logistic回归分析判定,NLR、BNP和hs-CRP是影响患者预后的独立危险因素。NLR、BNP和hs-CRP单一及联合监测的AUC分别是0.902、0.796、0.853、0.952,具有较高的预测价值。结论NLR、BNP、hs-CRP联合检测对老年肺部感染患者的预后评估有较高的参考意义,有助于改善患者预后。Objective To study the role of neutrophil and lymphocyte ratio(NLR),blood type B brain natriuretic peptide(BNP)and hypersensitive C-reactive protein(hs-CRP)in evaluating the prognosis of elderly patients with community-acquired pneumonia.Methods The clinical data of ninety-one elderly patients with community-acquired pneumonia admitted to Second People's Hospital of Lai'an County from January to December 2023 were retrospectively selected.According to the prognosis and discharge follow-up,the patients were divided into good group(n=44)and general group(n=47).The independent risk factors affecting the prognosis of elderly patients with community-acquired pneumonia were determined by univariate and multivariate logistic regression analysis.The ROC curve was drawn,and the predictive value was analyzed according to AUC,sensitivity and specificity.Results Univariate analysis showed that the levels of NLR,BNP and hs-CRP in the good group were lower than those in the general group,and the hospitalization days were less than those in the general group,with statistically significant differences(all P<0.05).Multivariate Logistic regression analysis showed that NLR,BNP and hs-CRP were independent risk factors affecting the prognosis of patients.The AUC areas of NLR,BNP and hs-CRP single and combined tests were 0.902,0.796,0.853 and 0.952,respectively,which had high predictive value.Conclusion The combined detection of NLR,BNP and hs-CRP has a high reference value for the prognosis evaluation of elderly patients with pulmonary infection,which is helpful to improve the prognosis of patients.

关 键 词：中性粒细胞与淋巴细胞比值 血B型脑钠肽 超敏C反应蛋白 老年肺部感染 

分 类 号：R541.6[医药卫生—心血管疾病] R563.1[医药卫生—内科学]