盐酸氨溴索加盐酸丙卡特罗治疗小儿肺炎效果分析  

Analysis of the Therapeutic Effect of Ambroxol Hydrochloride Combined with Procaterol Hydrochloride in the Treatment of Pediatric Pneumonia

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作  者:罗永丽 LUO Yongli(Department of Pediatrics,Meitan County People's Hospital,Zunyi 564100,Guizhou,China)

机构地区:[1]湄潭县人民医院儿科,贵州遵义564100

出  处:《系统医学》2025年第4期137-140,共4页Systems Medicine

摘  要:目的分析盐酸氨溴索联合盐酸丙卡特罗在小儿肺炎治疗中的临床应用效果。方法非随机选取2020年4月—2023年7月湄潭县人民医院儿科收治的100例肺炎患儿为研究对象。研究对象按治疗方案不同分为对照组和观察组,各包含50例患者。对照组接受常规治疗,而观察组在此基础上额外使用盐酸氨溴索和盐酸丙卡特罗进行干预。比较两组患儿治疗效果、气道功能、症状消退时间及肺功能指标。结果观察组治疗总有效率为96.00%(48/50),高于对照组的84.00%(42/50),差异有统计学意义(χ^(2)=4.000,P<0.05)。治疗后,观察组呼出25%肺活量流速、呼出50%肺活量流速、呼出75%肺活量流速均高于对照组,差异有统计学意义(P均<0.05)。观察组肺啰音、咳嗽、发热、气喘等症状消退时间均较对照组更短,差异有统计学意义(P均<0.05)。观察组第一秒用力呼气的容积、用力肺活量、第一秒内呼出的空气量与呼出的空气总量之比均较对照组更高,差异有统计学意义(P均<0.05)。结论联合用药可提升患儿治疗效果,尽早消退各临床症状,改善气道功能以及肺功能,值得临床借鉴。Objective To analyze the clinical application effect of ambroxol hydrochloride combined with procaterol hydrochloride in the treatment of pneumonia in children.Methods A total of 100 children with pneumonia admitted to the Department of Pediatrics of Meitan County People's Hospital from April 2020 to July 2023 were non-randomly selected as the research objects.The subjects were divided into control group and observation group according to different treatment regimens,each containing 50 patients.The control group received routine treatment,while the observation group received additional intervention with ambroxol hydrochloride and procaterol hydrochloride on this basis.The overall therapeutic effect,airway function,symptoms resolution time and lung function indexes were compared between the two groups.Results The observation group achieved an overall effective rate of 96.00%(48/50),notably surpassing the 84.00%(42/50)recorded for the control group.which was higher than 84.00%(42/50)of the control group,the difference was statistically significant(χ^(2)=4.000,P<0.05).After treatment,the 25%,50%and 75%exhaled flow rates in observation group were higher than those in control group,and the differences were statistically significant(all P<0.05).The regression time of pulmonary rales,cough,fever and asthma in the observation group was shorter than that in the control group,and the differences were statistically significant(all P<0.05).The volume of forced exhalation in the first second,forced vital capacity and the ratio of exhaled air to total exhaled air in the first second in the observation group were higher than those in the control group,and the differences were statistically significant(all P<0.05).Conclusion The combination therapy can improve the treatment effect of children,eliminate the clinical symptoms as soon as possible,improve the airway function and lung function,which is worthy of clinical reference.

关 键 词:盐酸氨溴索 肺功能 炎症反应 肺炎 免疫功能 盐酸丙卡特罗 

分 类 号:R725.6[医药卫生—儿科]

 

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