老年冠状动脉粥样硬化性心脏病患者诊断中应用血清胆红素联合血清尿酸检验的诊断价值分析  

Analysis of the Diagnostic Value of Applying Serum Bilirubin Combined with Serum Uric Acid Test in the Diagnosis of Elderly Patients with Coro⁃nary Atherosclerotic Heart Disease

作　　者：王士然 孔维红 梁婷玉 WANG Shiran;KONG Weihong;LIANG Tingyu(Department of Laboratory,Yanzhou District People′s Hospital,Jining 272100,Shandong,China)

机构地区：[1]兖州区人民医院检验科,山东济宁272100

出　　处：《系统医学》2025年第1期63-65,共3页Systems Medicine

摘　　要：目的研究血清胆红素联合血清尿酸检验诊断老年冠状动脉粥样硬化性心脏病(简称冠心病)患者的价值。方法非随机选取2021年1月—2022年12月济宁市兖州区人民医院收治的80例疑似老年冠心病患者为研究对象。患者均测定血清胆红素、血清尿酸水平。以临床冠状动脉造影检查结果作为诊断金标准,比较血清胆红素、血清尿酸单一与联合检验的诊断效能。结果冠状动脉造影检查诊断冠心病患者有52例。血清胆红素联合血清尿酸检验的准确度、灵敏度、特异度分别为98.75%(79/80)、100.00%(52/52)、96.43%(27/28),高于单一诊断,差异有统计学意义(χ^(2)=43.508、41.769、5.250,P均<0.05)。血清胆红素联合血清尿酸检验的Kappa值为0.972。结论在老年患者冠心病诊断中,实施血清胆红素联合血清尿酸检验,可有效提高疾病诊断的准确度。Objective To study the value of serum bilirubin combined with serum uric acid test for the diagnosis of coronary atherosclerotic heart disease(CHD)in elderly patients.Methods Eighty cases of suspected elderly patients with coronary heart disease admitted to Yanzhou District People′s Hospital in Jining City from January 2021 to De⁃cember 2022 were selected non-randomly as study subjects.Serum bilirubin and serum uric acid levels were mea⁃sured in all patients.The diagnostic efficacy of single and combined tests for serum bilirubin and serum uric acid was compared using the results of clinical coronary angiography as the gold standard for diagnosis.Results Coronary angi⁃ography was performed to diagnose coronary artery disease in 52 patients.The accuracy,sensitivity,and specificity of serum bilirubin combined with serum uric acid test were 98.75%(79/80),100.00%(52/52),and 96.43%(27/28),re⁃spectively,which were higher than those of the single diagnosis,and the differences were statistically significant(χ^(2)=43.508,41.769,5.250,all P<0.05).The Kappa value of serum bilirubin combined with serum uric acid test was 0.972.Conclusion Implementation of serum bilirubin combined with serum uric acid test in the diagnosis of coronary heart disease in elderly patients can effectively improve the accuracy of disease diagnosis.

关 键 词：冠状动脉粥样硬化性心脏病 血清胆红素 血清尿酸检验 诊断 准确度 

分 类 号：R541[医药卫生—心血管疾病]