经皮肝穿刺胆道引流联合腹腔镜手术治疗急性胆囊炎对患者疼痛及肝功能的影响  

Effect of percutaneous hepatic puncture biliary drainage combined with laparoscopic surgery on pain and liver function in patients with acute cholecystitis

作　　者：张杰 Zhang Jie(Department of General Surgery,Wuzhi People's Hospital,Wuzhi 454950,Henan,China)

机构地区：[1]武陟县人民医院普通外科,河南武陟454950

出　　处：《四川生理科学杂志》2025年第4期842-844,共3页

摘　　要：目的:探讨经皮肝穿刺胆道引流(PTCD)联合腹腔镜手术(LC)治疗急性胆囊炎(AC)对患者疼痛及肝功能的影响。方法:选择2022年5月至2024年5月期间本院收治的AC患者70例作为研究对象。采用随机数字表法将患者分为对照组和观察组,每组各35例。对照组行LC治疗;观察组采用PTCD联合LC治疗。分析比较两组的围术期指标、肝功能[总胆红素(TBIL)、谷草转氨酶(AST)及谷丙转氨酶(ALT)]及并发症。结果:观察组的手术时间、术后恢复时间均显著短于对照组,疼痛评分显著低于对照组(P<0.05)。治疗前,两组TBIL、AST、ALT各项肝功能指标均无显著差异(P>0.05)。治疗后,两组的TBIL、AST、ALT均比治疗前显著降低,且观察组的TBIL、AST、ALT显著低于对照组(P<0.05)。观察组的并发症发生率显著低于对照组(P<0.05)。结论:AC患者采用PTCD联合LC治疗,能缩短手术时间,促进术后恢复,减轻术后疼痛,促进肝功能恢复,减少术后并发症。Objective:To investigate the effects of percutaneous hepatic puncture biliary drainage(PTCD)combined with laparoscopic surgery(LC)on pain and liver function in patients with acute cholecystitis(AC).Methods:70 patients with AC admitted to our hospital from May 2022 to May 2024 were selected as the study objects.Patients were divided into control group and observation group by random number table method,with 35 cases in each group.The control group received LC treatment;Observation group was treated with PTCD combined with LC.The perioperative indexes,liver function[total bilirubin(TBIL),aspartate aminotransferase(AST)and alanine aminotransferase(ALT)]and complications of the two groups were analyzed and compared.Results:The operation time and postoperative recovery time of the observation group were significantly shorter than that of the control group,and the pain score was significantly lower than that of the control group(P<0.05).Before treatment,there were no significant differences in liver function indexes of TBIL,AST and ALT between the two groups(P>0.05).After treatment,TBIL,AST and ALT in both groups were significantly lower than before treatment,and TBIL,AST and ALT in the observation group were significantly lower than those in the control group(P<0.05).The complication rate of the observation group was significantly lower than that of the control group(P<0.05).Conclusion:PTCD combined with LC in AC patients can shorten operation time,promote postoperative recovery,relieve postoperative pain,promote liver function recovery and reduce postoperative complications.

关 键 词：急性胆囊炎 经皮肝穿刺胆道引流 腹腔镜手术 肝功能 疼痛 

分 类 号：R657.4[医药卫生—外科学]