脓毒症患者重症医学病房住院期间下肢肌间静脉血栓发生情况及危险因素分析  

Analysis of incidence and risk factors of lower extremity muscular calf vein thrombosis in sepsis patients during intensive care unit hospitalization

作　　者：李莹莹[1] 金艳鸿[1] 闫春莉 王静亚 Li Yingying;Jin Yanhong;Yan Chunli;Wang Jingya(Department of Critical Care Medicine,Beijing Friendship Hospital,Capital Medical University,Beijing 101300,China;Department of Cardiovascular Surgery,Beijing Friendship Hospital,Capital Medical University,Beijing 101300,China)

机构地区：[1]首都医科大学附属北京友谊医院重症医学科,北京101300 [2]首都医科大学附属北京友谊医院心血管外科,北京101300

出　　处：《血管与腔内血管外科杂志》2025年第3期337-341,共5页Journal of Vascular and Endovascular Surgery

摘　　要：目的探讨脓毒症患者在重症医学病房(ICU)住院期间下肢肌间静脉血栓(MCVT)的发生情况及其相关危险因素。方法收集2021年1月至2023年10月首都医科大学附属北京友谊医院收治的201例脓毒症患者的临床资料,根据ICU住院期间下肢MCVT的发生情况将患者分为MCVT组(n=61)和对照组(n=140)。比较两组患者的临床特征和住院期间治疗情况,采用多因素Logistic回归模型分析脓毒症患者在ICU住院期间发生下肢MCVT的危险因素。结果MCVT组患者的年龄和体重指数均大于对照组患者,合并创伤、住院期间使用呼吸机的比例均高于对照组患者,差异均有统计学意义(P﹤0.05)。多因素分析结果显示,年龄≥60岁、肥胖[体重指数(BMI)≥28 kg/m^(2)]、合并创伤和住院期间使用呼吸机均是脓毒症患者在ICU住院期间发生下肢MCVT的独立危险因素(P﹤0.05)。结论脓毒症患者ICU住院期间发生下肢MCVT的比例较高,相关的危险因素包括年龄≥60岁、肥胖(体重指数≥28 kg/m^(2))、合并创伤和住院期间使用呼吸机。Objective To investigate the incidence and risk factors of lower extremity muscular calf vein thrombosis(MCVT)in sepsis patients during hospitalization in the intensive care unit(ICU).Method The clinical data of 201 sepsis patients admitted to Beijing Friendship Hospital,Capital Medical University from January 2021 to October 2023 were collected.The patients were divided into MCVT group(n=61)and control group(n=140)based on the occurrence of lower extremity MCVT during hospitalization in the ICU.The clinical characteristics and treatment status of two groups of patients during hospitalization were compared,and multiple Logistic regression model was used to analyze the risk factors for lower extremit MCVT in sepsis patients during ICU hospitalization.Result The age and body mass index(BMI)of patients in the MCVT group were greater than those in the control group,and the proportion of patients with concurrent trauma and using ventilators during hospitalization were higher than those in the control group,the differences were statistically significant(P<0.05).The results of multivariate analysis showed that age≥60 years old,obesity(BMI≥28 kg/m^(2)),concurrent trauma,and use of ventilators during hospitalization were independent risk factors for lower extremity MCVT in sepsis patients during hospitalization in the ICU(P<0.05).Conclusion The proportion of sepsis patients hospitalized in the ICU who develop lower extremity MCVT is relatively high,and related risk factors include age≥60 years old,obesity(BMI≥28 kg/m^(2)),concurrent trauma,and use of ventilators during hospitalization in the ICU.

关 键 词：脓毒症 重症医学病房 肌间静脉血栓 危险因素 

分 类 号：R543[医药卫生—心血管疾病]