金线莲提取物安全性与化妆品应用研究  

Study on the safety and cosmetic application of Anoectochilus roxburghii extract

作　　者：陈冬杰 陈来成 邹洁 李泳棋 刘晓纯 沈国锋 CHEN Dongjie;CHEN Laicheng;ZOU Jie;LI Yongqi;LIU Xiaochun;SHEN Guofeng(Guangzhou Hemgathion Biotechnology Co.,Ltd,Guangzhou,Guangdong 510800,China;Fujian Jingzhilian Biotechnology Co.,Ltd,Zhangzhou,Fujian 363000,China;College of Chemistry and Chemical Engineering,Guangdong Pharmaceutical University,Zhongshan,Guangdong 528458,China)

机构地区：[1]广州麻尚会生物科技有限公司,广东广州510800 [2]福建靖芝莲生物科技有限公司,福建漳州363000 [3]广东药科大学医药化工学院,广东中山528458

出　　处：《日用化学品科学》2025年第4期64-69,共6页Detergent & Cosmetics

基　　金：金线莲深加工与化妆品应用研究与产业化(2023440111002747)。

摘　　要：为探究金线莲在化妆品中的应用,合理开发金线莲化妆品,将金线莲全株植物进行提取开发并应用到化妆品中,并对其安全性与功效性展开研究。结果表明,金线莲提取物安全无毒害,对皮肤无刺激性,高温和光照条件会使金线莲提取物中部分活性成分有所下降。金线莲提取物能够提高柔肤水产品的酪氨酸酶抑制率、DPPH自由基抑制率与ABTS自由基抑制率,具有良好的抗氧化、美白及舒缓保湿功效。此外,在使用金线莲柔肤水28 d后,受试区域的角质层水分含量上升了50.24%,红区面积占比和血红素含量分别下降了32.05%和27.63%,金线莲柔肤水具有良好的舒缓保湿效果。In order to explore the application of Anoectochilus roxburghii in cosmetics and rationally develop A.roxburghii cosmetics,the whole plant of A.roxburghii was extracted,developed and applied to cosmetics products,and its safety and efficacy were studied.The results showed that the extract of A.roxburghii was safe and non-toxic,and it had no irritation to the skin.The high temperature and light conditions would reduce the content of some active ingredients in the extract of A.roxburghii.The extract of A.roxburghii can improve the tyrosinase inhibition rate,DPPH free radical inhibition rate and ABTS free radical inhibition rate of soft skin water products,which has good antioxidant,whitening and soothing moisturizing effects.In addition,after 28 days of using A.roxburghii lotion,the water content of stratum corneum in the test area was increased by 50.24%,the proportion of red area and hemoglobin content was decreased by 32.05%and 27.63%,respectively.A.roxburghii lotion has a good soothing and moisturizing effect.

关 键 词：金线莲提取物 金线莲化妆品 舒缓保湿 抗氧化 美白 

分 类 号：TQ658[化学工程—精细化工]