氧合指数与APACHEⅡ评分在慢性阻塞性肺疾病伴呼吸衰竭患者中的应用价值研究  

Study on application value of oxygenation index and APACHEⅡscore in treatment of patients with chronic obstructive pulmonary disease and respiratory failure

作　　者：武历梅 徐华兵 WU Li-mei;XU Hua-bing(Emergency ICU,Caoxian County People's Hospital,Heze 274400,China)

机构地区：[1]曹县人民医院急诊ICU,274400

出　　处：《中国现代药物应用》2025年第6期37-40,共4页Chinese Journal of Modern Drug Application

摘　　要：目的评估在慢性阻塞性肺疾病伴呼吸衰竭患者中应用氧合指数、急性生理学与慢性健康状况评分系统Ⅱ(APACHEⅡ)评分的作用。方法88例慢性阻塞性肺疾病伴呼吸衰竭患者,根据随机数字表法分为参照组与研究组,每组44例。参照组给予常规干预,研究组在常规干预的基础上进行氧合指数与APACHEⅡ评分预测管理。对比两组机械通气时间、重症加强护理病房(ICU)住院时间、APACHEⅡ评分、氧合指数、呼吸频率、潮气量、呼吸机相关性肺炎发生率。结果研究组机械通气时间(7.01±0.21)d、ICU住院时间(8.96±1.26)d短于参照组的(8.98±1.21)、(13.04±1.62)d(P<0.05)。机械通气第7天,研究组的APACHEⅡ评分(12.16±2.11)分低于参照组的(14.67±2.13)分(P<0.05)。机械通气第7天,两组的氧合指数、潮气量高于机械通气第1天,呼吸频率低于机械通气第1天,且研究组的氧合指数(412.12±7.82)mm Hg(1 mm Hg=0.133 kPa)、潮气量(8.37±1.01)ml/kg高于参照组的(361.61±9.84)mm Hg、(7.61±1.08)ml/kg,呼吸频率(19.32±2.72)次/min低于参照组的(22.32±2.17)次/min(P<0.05)。研究组呼吸机相关性肺炎发生率为2.27%,低于参照组的15.91%(χ^(2)=4.950,P=0.026<0.05)。结论氧合指数与APACHEⅡ评分在慢性阻塞性肺疾病伴呼吸衰竭患者治疗中具有较好的预测作用,有利于缩短机械通气时间,改善肺功能,应用价值高。Objective To evaluate the role of oxygenation index and acute physiology and chronic health evaluationⅡ(APACHEⅡ)score in treatment of patients with chronic obstructive pulmonary disease and respiratory failure.Methods 88 patients with chronic obstructive pulmonary disease and respiratory failure were divided into reference group and study group according to random numerical table,with 44 cases in each group.The reference group was given conventional intervention,and the study group was given predictive management of oxygenation index and APACHEⅡscore on the basis of conventional intervention.Both groups were compared in terms of duration of mechanical ventilation,length of intensive care unit(ICU)stay,APACHEⅡscore,oxygenation index,respiratory rate,tidal volume and incidence of ventilators-associated pneumonia.Results In the study group,the duration of mechanical ventilation was(7.01±0.21)d and the length of ICU stay was(8.96±1.26)d,which were shorter than(8.98±1.21)and(13.04±1.62)d in the reference group(P<0.05).On the 7th day of mechanical ventilation,the APACHEⅡscore of the study group was(12.16±2.11)points,which was lower than(14.67±2.13)points in the reference group(P<0.05).On the 7th day of mechanical ventilation,the oxygenation index and tidal volume in both groups were higher than those on the 1st day of mechanical ventilation,and the respiratory rate was lower than that on the 1st day of mechanical ventilation;the oxygenation index and tidal volume in the study group were(412.12±7.82)mm Hg(1 mm Hg=0.133 kPa)and(8.37±1.01)ml/kg,which were higher than(361.61±9.84)mm Hg and(7.61±1.08)ml/kg in the reference group;the study group had a lower respiratory rate of(19.32±2.72)times/min than(22.32±2.17)times/min in the reference group(P<0.05).The incidence of ventilators-associated pneumonia in the study group was 2.27%,which was lower than 15.91%in the reference group(χ^(2)=4.950,P=0.026<0.05).Conclusion Oxygenation index and APACHEⅡscore have a good predictive effect in the treatment of

关 键 词：慢性阻塞性肺疾病 呼吸衰竭 氧合指数 急性生理学与慢性健康状况评分系统Ⅱ评分 

分 类 号：R563[医药卫生—呼吸系统] R563.9[医药卫生—内科学]