轮叶党参草本粉对产后催乳通乳的临床有效性和安全性研究  

Study on the clinical effectiveness and safety of codonopsis lanceolata herbal powder for postpartum lactation promotion

作　　者：韩小雪[1] 王兴和[2] 李瑞满[1] HAN Xiao-xue;WANG Xing-he;LI Rui-man(The First Affiliated Hospital of Jinan University,Guangzhou 510000,China)

机构地区：[1]暨南大学附属第一医院产科,510000 [2]东莞市妇幼保健院,523110

出　　处：《中国现代药物应用》2025年第6期132-136,共5页Chinese Journal of Modern Drug Application

摘　　要：目的探讨轮叶党参草本粉对产后催乳通乳的临床有效性和安全性。方法采取随机对照、单盲的临床研究,共纳入95例产妇,随机分为试验组(采用轮叶党参草本粉治疗,51例)和对照组(采用轮叶党参草本粉安慰剂治疗,44例)。比较两组产妇基线资料及产后泌乳情况,并评价安全性。结果共纳入95例产妇,产后第7天收集回访信息表81份(试验组41份,对照组40份),产后第14天收集回访信息表81份(试验组40份,对照组41份),产后第30天收集回访信息表65份(试验组29份,对照组36份)。产后第7、14、30天两组年龄、身高、胎次及分娩方式比较均无统计学差异(P>0.05)。产后第7、14天,试验组挤压乳房乳汁通畅且有乳汁喷射占比82.93%和90.00%明显高于对照组的55.00%和68.29%,添加奶粉占比68.29%和35.00%明显低于对照组的87.50%和75.61%,有统计学差异(P<0.05);两组每24小时哺乳次数≥8次且婴儿吸吮时有吞咽声、每天换尿片≥6次且有少量多次大便、两次哺乳期间婴儿安静不哭闹、哺乳前有乳房涨感且哺乳时有射乳反射、乳房硬结/红肿/热痛且伴有发热占比比较均无统计学差异(P>0.05)。产后第30天,试验组哺乳前有乳房涨感且哺乳时有射乳反射占比89.66%明显高于对照组的58.33%,添加奶粉占比37.93%明显低于对照组的83.33%,有统计学差异(P<0.05);两组每24小时哺乳次数≥8次且婴儿吸吮时有吞咽声、每天换尿片≥6次且有少量多次大便、两次哺乳期间婴儿安静不哭闹、乳房硬结/红肿/热痛且伴有发热、挤压乳房乳汁通畅且有乳汁喷射占比比较均无统计学差异(P>0.05)。本研究过程中未发生不良反应。结论轮叶党参草本粉通乳催乳的效果明显,有助于促进母乳喂养。Objective To explore the clinical effectiveness and safety of codonopsis lanceolata herbal powder for postpartum lactation promotion.Methods A randomized controlled,single-blind clinical study was conducted.A total of 95 parturients were included and randomly divided into the experimental group(codonopsis lanceolata herbal powder,51 cases)and the control group(placebo of codonopsis lanceolata herbal powder,44 cases).The baseline data and postpartum lactation were compared between the two groups,and safety was evaluated.Results A total of 95 cases were enrolled and 81 return information forms(41 forms in the test group and 40 forms in the control group)were collected on postpartum day 7,81 forms on postpartum day 14(40 forms in the experimental group and 41 forms in the control group)and 65 on postpartum day 30(29 forms in the experimental group and 36 forms in the control group).There were no statistical differences in age,height,parity and mode of delivery between the two groups on postpartum days 7,14 and 30(P>0.05).On postpartum days 7 and 14,the percentages of smooth milk flow and milk ejection when squeezing the breast were 82.93%and 90.00%in the experimental group,which were obviously higher than 55.00%and 68.29%in the control group;the percentages of adding milk powder were 68.29%and 35.00%,which were obviously lower than 87.50%and 75.61%in the control group;there were statistical differences(P<0.05).There was no statistically significant difference between the two groups when comparing the percentage of≥8 breastfeedings per 24-h with swallowing sound,≥6 diaper changes per day with small and frequent stools,quiet and no crying during the two breastfeeding periods,feeling of breast rise before breastfeeding and ejaculation reflex during breastfeeding,and hardness/redness/hotness/pain in the breasts accompanied by fever(P>0.05).On postpartum day 30,89.66%of the experimental group had a feeling of breast rise before breastfeeding and ejaculation reflex during breastfeeding, which was significantly higher

关 键 词：轮叶党参草本粉 产后 催乳通乳 

分 类 号：R271.43[医药卫生—中医妇科学]