血浆乳酸联合血浆致动脉硬化指数对原发性高血压患者早期肾损害的预测价值  

Predictive Value of Plasma Lactate Combined with Plasma Atherogenic Index for Early Renal Damage in Patients with Essential Hypertension

作　　者：古孜丽努尔·马木提 Guziinuer·Mamuti(Department of Hypertension and Cardiac Electrophysiology,Bortala Mongolian Autonomous Prefecture People’s Hospital,Bortala 833400,China)

机构地区：[1]博尔塔拉蒙古自治州人民医院高血压与心肌电科,新疆博尔塔拉833400

出　　处：《反射疗法与康复医学》2025年第5期128-131,共4页Reflexology And Rehabilitation Medicine

摘　　要：目的 分析血浆乳酸联合血浆致动脉硬化指数对原发性高血压患者早期肾损害的预测价值。方法 选取2023年1月—2024年9月博尔塔拉蒙古自治州人民医院收治的100例原发性高血压患者为研究对象,根据是否发生早期肾损害将其分为A组(发生早期肾损害,n=38)与B组(未发生早期肾损害,n=62)。两组均采用血浆乳酸联合血浆致动脉硬化指数检测。对比两组的血浆乳酸、血浆致动脉硬化指数其阳性检出率,并评估其早期肾损害的预测价值。结果 A组血浆乳酸水平、血浆致动脉硬化指数均高于B组,组间差异有统计学意义(P<0.05)。A组血浆乳酸、血浆致动脉硬化指数阳性检出率均高于B组,组间差异有统计学意义(P<0.05)。血浆乳酸、血浆致动脉硬化指数联合检测对早期肾损害预测的准确率、敏感度、阴性预测值均优于血浆乳酸、血浆致动脉硬化指数的单项检测,差异有统计学意义(P<0.05);血浆乳酸、血浆致动脉硬化指数联合检测对早期肾损害预测的特异度、阳性预测值与血浆乳酸、致动脉硬化指数单项检测对比,差异无统计学意义(P>0.05)。结论 血浆乳酸联合血浆致动脉硬化指数对原发性高血压患者早期肾损害的预测价值较高,优于单项检测,可为临床诊治提供可靠的参考依据,具有一定的临床应用意义。Objective Analyze the predictive value of plasma lactate combined with the plasma atherogenic index for early renal damage in patients with essential hypertension.Methods A total of 100 patients with essential hypertension admitted to Bortala Mongolian Autonomous Prefecture People’s Hospital from January 2023 to September 2024 were selected as the research subjects,according to whether early renal damage occurred or not,they were divided into a Group A(with early renal damage,n=38)and a Group B(without early renal damage,n=62),both groups were detected by plasma lactate combined with the plasma atherogenic index.The plasma lactate,plasma atherogenic index and their positive detection rates were compared between the two groups,and the predictive value for early renal damage was evaluated.Results The levels of plasma lactate and the plasma atherogenic index in the Group A were both higher than those in the Group B,and the differences between the two groups were statistically significant(P<0.05).The positive detection rates of plasma lactate and the plasma atherogenic index in the Group A were both higher than those in the Group B,and the differences between the two groups were statistically significant(P<0.05).The accuracy rate,sensitivity,and negative predictive value of the combined detection of plasma lactate and the plasma atherogenic index for the prediction of early renal damage were all better than those of the single detection of plasma lactate and the plasma atherogenic index,and the differences were statistically significant(P<0.05),there were no statistically significant differences in the specificity and positive predictive value for the prediction of early renal damage between the combined detection of plasma lactate and the plasma atherogenic index and the single detection of plasma lactate and the plasma atherogenic index(P>0.05).Conclusion The combination of plasma lactate and the plasma atherogenic index has a relatively high predictive value for early renal damage in patients with essential hype

关 键 词：原发性高血压 早期肾损害 血浆乳酸 血浆致动脉硬化指数 预测价值 

分 类 号：R544.1[医药卫生—心血管疾病]