腹膜透析与血液透析治疗对终末期糖尿病肾病患者的肾功能及血压水平的影响对比  

Comparison of Effects of Peritoneal Dialysis and Hemodialysis on the Renal Function and Blood Pressure Levels of Patients with End-Stage Diabetic Nephropathy

作　　者：吴云霞[1] WU Yunxia(Department of Nephrology,The First People’s Hospital of Tianshui City,Tianshui 741000,China)

机构地区：[1]天水市第一人民医院肾病内科,甘肃天水741000

出　　处：《反射疗法与康复医学》2025年第5期140-143,共4页Reflexology And Rehabilitation Medicine

摘　　要：目的 探讨腹膜透析与血液透析治疗在终末期糖尿病肾病患者中的应用价值。方法 回顾性分析2022年1月—2024年1月天水市第一人民医院收治的86例终末期糖尿病肾病患者的病历资料,根据透析方式的不同将其分为对照组和观察组,每组43例。对照组采用血液透析治疗,观察组采用腹膜透析治疗,两组均持续治疗6个月。比较两组的肾功能指标、血压水平、钙磷代谢、血清炎性因子、不良事件发生情况。结果 治疗后,观察组收缩压、舒张压、尿素氮、血肌酐、血磷、C-反应蛋白、肿瘤坏死因子α、白细胞介素-6水平均低于对照组,血钙水平高于对照组,组间差异有统计学意义(P<0.05)。观察组不良事件发生率为6.98%,低于对照组的23.26%,差异有统计学意义(P<0.05)。结论 相较于血液透析,腹膜透析改善终末期糖尿病肾病患者肾功能的效果更为显著,可调节患者的血压水平,平衡钙磷代谢,降低炎性因子水平,且不良事件发生率较低。Objective To explore the application value of peritoneal dialysis and hemodialysis in the treatment of patients with end-stage diabetic nephropathy.Methods A retrospective analysis was conducted on the medical records of 86 patients with end-stage diabetic nephropathy admitted to the First People’s Hospital of Tianshui City from January 2022 to January 2024,according to the different dialysis methods,the patients were divided into a control group and an observation group,with 43 cases in each group.The control group was treated with hemodialysis,and the observation group was treated with peritoneal dialysis,both groups were treated continuously for 6 months.The renal function indicators,blood pressure levels,calcium and phosphorus metabolism,serum inflammatory factors,and the occurrence of adverse events were compared between the two groups.Results After treatment,the levels of systolic blood pressure,diastolic blood pressure,blood urea nitrogen,serum creatinine,serum phosphorus,C-reactive protein,tumor necrosis factor-α,and interleukin-6 in the observation group were all lower than those in the control group,while the level of serum calcium was higher than that in the control group,and the differences between the two groups were statistically significant(P<0.05).The incidence of adverse events in the observation group was 6.98%,which was lower than 23.26%in the control group,and the difference was statistically significant(P<0.05).Conclusion Compared with hemodialysis,peritoneal dialysis has a more significant effect in improving the renal function of patients with end-stage diabetic nephropathy.It can regulate the patients’blood pressure levels,balance the metabolism of calcium and phosphorus,reduce the levels of inflammatory factors,and has a lower incidence of adverse events.

关 键 词：终末期糖尿病肾病 腹膜透析 血液透析 肾功能 血压 

分 类 号：R587.24[医药卫生—内分泌]