脓毒性休克患者并发急性肾损伤的多因素Logistic回归分析  

Multivariate Logistic Regression Analysis of Septic Shock Patients Complicated with Acute Kidney Injury

作　　者：宋海燕 SONG Haiyan(Department of NO.1 Intensive Care Medicine,Third People’s Hospital of Jinan,Jinan 250132,China)

机构地区：[1]济南市第三人民医院重症医学一科,山东济南250132

出　　处：《反射疗法与康复医学》2025年第7期98-100,104,共4页Reflexology And Rehabilitation Medicine

摘　　要：目的分析脓毒性休克(SS)患者并发急性肾损伤(AKI)的影响因素。方法回顾性分析2022年7月—2024年7月济南市第三人民医院收治的120例SS患者的临床资料,根据是否并发AKI将其分为并发组与未并发组,采用多因素Logistic回归分析SS患者并发AKI的危险因素。结果120例SS患者中,共有12例并发AKI,AKI并发率为10.00%(12/120)。单因素分析显示,两组吸烟史、高血压、糖尿病、机械通气、输血史、细菌培养结果、MAP比较,组间差异有统计学意义(P<0.05)。Logistic回归分析显示,有吸烟史(OR=6.739,95%CI=1.409~32.243)、有高血压(OR=4.171,95%CI=1.176~14.796)、有糖尿病(OR=5.526,95%CI=1.411~21.640)、有机械通气(OR=8.846,95%CI=1.844~42.441)、有输血史(OR=4.902,95%CI=1.254~19.162)、细菌培养阳性(OR=9.211,95%CI=1.919~44.215)、平均动脉压(MAP)<70 mmHg(OR=6.529,95%CI=1.662~25.652)是导致SS患者并发AKI的独立危险因素(P<0.05)。结论影响SS患者并发AKI的危险因素众多,如有吸烟史、有高血压、有糖尿病、有机械通气、有输血史、细菌培养阳性、MAP<70 mmHg。Objective To analyze the influencing factors of acute kidney injury(AKI)in patients with septic shock(SS).Methods The clinical data of 120 SS patients admitted to Jinan Third People’s Hospital from July 2022 to July 2024 were retrospectively analyzed.The patients were divided into the complicated group and the non-complicated group according to whether they were complicated with AKI.Multivariate Logistic regression analysis was used to explore the risk factors of SS patients complicated with AKI.Results Among the 120 patients with SS,12 patients were complicated with AKI,and the complication rate of AKI was 10.00%(12/120).Univariate analysis showed that there were statistically significant differences in smoking history,hypertension,diabetes,mechanical ventilation,blood transfusion history,bacterial culture results,and MAP between the two groups(P<0.05).Logistic regression analysis showed that smoking history(OR=6.739,95%CI=1.409~32.243),hypertension(OR=4.171,95%CI=1.176~14.796),diabetes(OR=5.526,95%CI=1.411~21.640),mechanical ventilation(OR=8.846,95%CI=1.844~42.441),history of blood transfusion(OR=4.902,95%CI=1.254~19.162),positive bacterial culturee(OR=9.211,95%CI=1.919~44.215),mean arterial pressure(MAP)<70 mmHg(OR=6.529,95%CI=1.662~25.652)were independent risk factor for AKI in SS patients(P<0.05).Conclusion There are many risk factors influencing AKI in SS patients,such as smoking history,hypertension,diabetes,mechanical ventilation,blood transfusion history,positive bacterial culture,MAP<70 mmHg。

关 键 词：脓毒性休克 急性肾损伤 危险因素 

分 类 号：R631[医药卫生—外科学]