输尿管软镜钬激光碎石取石术与经皮肾镜碎石取石术治疗对肾结石患者肾功能、应激指标的影响对比  

Comparison of Effects of Flexible Ureteroscopic Holmium Laser Lithotripsy and Percutaneous Nephrolithotripsy on Renal Function and Stress Indicators in Patients with Kidney Stones

作　　者：赵计伟 ZHAO Jiwei(Department of Urology,Pizhou Hospital Affiliated to Xuzhou Medical University,Xuzhou 221300,China)

机构地区：[1]徐州医科大学附属邳州医院泌尿外科,江苏徐州221300

出　　处：《反射疗法与康复医学》2025年第2期101-104,共4页Reflexology And Rehabilitation Medicine

摘　　要：目的探讨输尿管软镜钬激光碎石取石术(FURS)与经皮肾镜碎石取石术(PCNL)治疗对肾结石患者的影响。方法回顾性分析2021年3月—2022年10月徐州医科大学附属邳州医院收治的80例肾结石患者的病历资料,根据手术方式不同将其分为对照组(n=40)和观察组(n=40)。对照组行PCNL治疗,观察组行FURS治疗。比较两组的围术期指标、肾功能指标、应激指标、结石清除率及并发症发生情况。结果观察组手术时间为(94.58±7.63)min,长于对照组的(78.04±6.85)min,术中出血量为(4.85±0.49)mL,少于对照组的(12.58±1.34)mL,住院时间为(4.69±1.12)d,短于对照组的(6.41±1.15)d,组间有统计学差异(P<0.05);观察组术后BUN、CysC、Scr水平分别为(10.35±1.22)mmol/L、(613.41±50.28)μg/L、(86.04±6.75)μmol/L,低于对照组的(12.33±1.34)mmol/L、(681.71±52.35)μg/L、(92.81±7.24)μmol/L,组间有统计学差异(P<0.05);观察组术后NE、ACTH、Cor水平分别为(225.63±22.35)ng/mL、(37.33±3.45)ng/L、(112.65±10.34)nmol/L,低于对照组的(269.78±24.53)ng/mL、(45.43±4.18)ng/L、(129.41±12.57)nmol/L,组间有统计学差异(P<0.05);两组结石清除率、并发症发生率对比,组间差异无统计学意义(P>0.05)。结论FURS与PCNL在肾结石治疗中均具有较高的价值,但FURS可减轻机体损害,更好地保护患者的肾功能,值得推广。Objective Exploring the effects of flexible ureteroscopic holmium laser lithotripsy(FURS)and percutaneous nephrolithotripsy(PCNL)on patients with kidney stones.Methods The medical records of 80 patients with kidney stones treated in Pizhou Hospital Affiliated to Xuzhou Medical University from March 2021 to October 2022 were retrospectively analyzed,according to different surgical methods,they were divided into a control group(n=40)and an observation group(n=40).The control group was treated with PCNL,and the observation group was treated with FURS.The perioperative indicators,renal function indicators,stress indicators,stone clearance rate and occurrence of complications were compared between the two groups.Results The operation time of the observation group was(94.58±7.63)minutes,which was longer than(78.04±6.85)minutes of the control group,the intraoperative blood loss was(4.85±0.49)milliliters,which was less than(12.58±1.34)milliliters of the control group,the length of hospital stay was(4.69±1.12)days,which was shorter than(6.41±1.15)days of the control group,and the differences between the two groups were statistically significant(P<0.05);the levels of BUN,CysC,and Scr in the observation group after surgery were(10.35±1.22)mmol/L,(613.41±50.28)μg/L,and(86.04±6.75)μmol/L respectively,which were lower than(12.33±1.34)mmol/L,(681.71±52.35)μg/L,and(92.81±7.24)μmol/L in the control group,and the differences between the two groups were statistically significant(P<0.05);the levels of NE,ACTH,and Cor in the observation group after surgery were(225.63±22.35)ng/mL,(37.33±3.45)ng/L,and(112.65±10.34)nmol/L respectively,which were lower than(269.78±24.53)ng/mL,(45.43±4.18)ng/L,and(129.41±12.57)nmol/L in the control group,and the differences between the two groups were statistically significant(P<0.05).There was no significant difference in stone clearance rate and complication rate between the two groups(P>0.05).Conclusion Both FURS and PCNL have high value in the treatment of kidney stones,but FURS

关 键 词：肾结石 输尿管软镜钬激光碎石取石术 肾功能 应激指标 

分 类 号：R691.4[医药卫生—泌尿科学]