鱼腥草抗肺癌作用机制的研究进展  

Research progress on mechanism of anti-lung cancer effect of Houttuynia cordata Thunb

作　　者：宋新强 杨金燕 李杨 张岩 王佳慧 SONG Xinqiang;YANG Jinyan;LI Yang;ZHANG Yan;WANG Jiahui(College of Life Sciences,Xinyang Normal University,Xinyang 464000,China;College of Medicine,Xinyang Normal University,Xinyang 464000,China;College of International Education,Xinyang Normal University,Xinyang 464000,China;Department of Ultrasound,Xinyang Central Hospital,Xinyang 464000,China)

机构地区：[1]信阳师范大学生命科学学院,河南信阳464000 [2]信阳师范大学医学院,河南信阳464000 [3]信阳师范大学国际教育学院,河南信阳464000 [4]信阳市中心医院超声科,河南信阳464000

出　　处：《信阳师范大学学报(自然科学版)》2025年第2期239-248,共10页Journal of Xinyang Normal University(Natural Science Edition)

基　　金：国家自然科学基金项目(U1804179);河南省科技攻关计划项目(202102310190)。

摘　　要：鱼腥草是临床常见的药食同源药材,基于其良好的抗炎、抗肿瘤和免疫调节等活性,结合国内外关于鱼腥草治疗肺癌的相关研究进展,从抑制肺癌细胞侵袭和迁移、停滞肺癌细胞周期、诱导肺癌细胞自噬、介导肺癌细胞凋亡、抑制新生血管生成、抑制氧化应激、增强机体免疫功能、改善肺炎炎症反应、增强肺癌细胞对放化疗的敏感性等方面,对鱼腥草抗肺癌的潜在作用机制进行了系统的梳理,为鱼腥草在生物医药领域的深入研究和应用提供相关参考和指导。Houttuynia Thunb.is a commonly used medicinal and edible homologous medicinal material in clinical practice.The relevant research progress on Houttuynia cordata Thunb.was summarized in the treatment of lung cancer at home and abroad based on its good anti-inflammatory,anti-tumor,and immune regulatory activities,and the potential mechanisms of Houttuynia cordata Thunb.against lung cancer such as inhibiting the invasion and migration of lung cancer cells,arresting the cell cycle of lung cancer cells,inducing autophagy of lung cancer cells,mediating apoptosis of lung cancer cells,inhibiting angiogenesis,inhibiting oxidative stress,enhancing the immune function of the body,improving the inflammatory response of pneumonia,and enhancing the sensitivity of lung cancer cells to radiotherapy and chemotherapy,with a view to providing relevant references and guidance for the further research and application of Houttuynia cordata Thunb.in the biomedical field.

关 键 词：鱼腥草 肺癌 分子机制 研究进展 

分 类 号：R28[医药卫生—中药学]