儿童非食管嗜酸粒细胞性胃肠道疾病预后不良的危险因素研究进展  

Research progress on risk factors for poor prognosis in pediatric non-esophageal eosinophilic gastrointestinal disorder

作　　者：刘祥晖(综述) 陈秀奇(审校)[1] LIU Xiang-Hui;CHEN Xiu-Qi(Department of Pediatrics,First Affiliated Hospital of Guangxi Medical University,Nanning 530021,China)

机构地区：[1]广西医科大学第一附属医院儿科,广西南宁530021 [2]河池市第一人民医院新生儿科,广西河池546300

出　　处：《中国当代儿科杂志》2025年第4期493-499,共7页Chinese Journal of Contemporary Pediatrics

基　　金：广西儿科疾病临床医学研究中心(桂科AD22035219);广西医科大学第一附属医院优秀英才计划项目。

摘　　要：非食管嗜酸粒细胞性胃肠道疾病(non-esophageal eosinophilic gastrointestinal disorder,non-EoE EGID)是一组以嗜酸性粒细胞浸润为特征的免疫介导的消化系统疾病。尽管多数患者在治疗后症状得到缓解,但仍有部分患者面临症状持续或复发的风险,改善这部分患者的预后是亟待解决的挑战,识别影响non-EoE EGID预后的危险因素并及时给予有效干预,对改善预后具有重要意义。该文对遗传因素、过敏、环境因素、临床特征、内镜表现、病理表现等与儿童non-EoE EGID预后相关的危险因素进行综述,以期为临床决策提供参考。Non-esophageal eosinophilic gastrointestinal disorder(non-EoE EGID)is a group of immune-mediated gastrointestinal diseases characterized by infiltration of eosinophils.Although most patients experience symptom relief after treatment,some still face the risk of persistent symptoms or relapse.Improving the prognosis for this subset of patients remains an urgent challenge.Identifying risk factors that affect the prognosis of non-EoE EGID and providing timely effective interventions are crucial for improving outcomes.This paper reviews the risk factors related to the prognosis of pediatric non-EoE EGID,including genetic factors,allergies,environmental factors,clinical characteristics,endoscopic findings,and pathological manifestations,with the aim of providing references for clinical decision-making.

关 键 词：嗜酸粒细胞性胃肠道疾病 预后 危险因素 儿童 

分 类 号：R725.7[医药卫生—儿科]