1990-2019年海南省感染性心内膜炎疾病负担及变化趋势分析  

Disease burden by infective endocarditis and trend in Hainan,1990-2019

作　　者：陈赛苦 朱瑞轩 乔利春 郭顺杰 文欣悦 王兴任 江娟 周脉耕[4] 刘莹 何滨 韩晶 Chen Saiku;Zhu Ruixuan;Qiao Lichun;GuoShunjie;Wen Xinyue;Wang Xingren;Jiang Juan;Zhou Maigeng;Liu Ying;He Bin;Han Jing(Hainan Academy of Preventive Medicine,Hainan Provincial Centre for Disease Control and Prevention,Haikou 570203,Hainan,China;The First Clinical Medical College of Xi'an Jiaotong University Health Science Center,Xi'an 710061,Shaanxi,China;School of Public Health,Xi'an Jiaotong University Health Science Center,Xi'an 710061,Shaanxi,China;National Center for Chronic and Non-communicable Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 100050,China)

机构地区：[1]海南省预防医学研究院,海南省疾病预防控制中心,海南海口570203 [2]西安交通大学医学部第一临床医学院,陕西西安710061 [3]西安交通大学医学部公共卫生学院,陕西西安710061 [4]中国疾病预防控制中心慢性非传染性疾病预防控制中心,北京100050

出　　处：《疾病监测》2025年第2期257-264,共8页Disease Surveillance

基　　金：陕西省环境科学研究院项目(No.02208146)。

摘　　要：目的分析1990—2019年海南省感染性心内膜炎(IE)疾病负担和变化趋势,为全省IE疾病防控工作提供基础依据。方法使用2019年全球疾病负担研究数据库中发病率、死亡率、伤残损失寿命年(YLD)、早死损失寿命年(YLL)和伤残调整寿命年(DALY)及其年龄标准化率等指标对1990—2019年海南省不同性别、年龄人群的IE疾病负担变化进行分析。计算年度变化百分比和平均年度变化百分比分析IE疾病负担变化趋势,并与全国IE情况进行比较。结果1990—2019年,海南省IE的年龄标化发病率(ASIR)和年龄标化YLD率(ASYLDR)呈上升趋势,年龄标化死亡率(ASMR)、年龄标化YLL率(ASYLLR)和年龄标化DALY率(ASDR)呈下降趋势。2019年,海南省IE的ASIR为15.14/10万,ASMR为0.27/10万。DALY、YLD、YLL分别为762.70人年、22.55人年和740.15人年,其年龄标化率分别为7.63/10万、0.23/10万、7.40/10万,其中YLL占DALY的97.04%。2019年海南省IE的ASDR、ASIR和ASMR均表现为男性高于女性。在不同年龄组中,≥95岁人群的发病率、死亡率和DALY率最高。1990—2019年,海南省IE的ASIR高于全国平均水平,其余疾病负担指标提示两者之间的差距正在不断缩小。结论1990—2019年海南省IE疾病负担整体呈下降趋势,其中ASIR和ASYLDR呈上升趋势。未来海南省ASIR可能继续呈上升趋势,应当加强对老年群体的关注和降低伤残所致的疾病负担。Objective To analyze the disease burden caused by infective endocarditis in Hainan province from 1990 to 2019 and provide evidence for the prevention and control of infective endocarditis in Hainan.Methods The data of Global Burden of Disease 2019(GBD 2019),including the incidence rate,mortality rate,years lived with disability(YLD),years of life lost(YLL),disability-adjusted of life years(DALY)of infective endocarditis and their age-standardized rates,were used to analyze the changes in the disease burden of infective endocarditis by gender and age in Hainan from 1990 to 2019.Annual percentage change(APC)and average annual percentage change(AAPC)were calculated to analyze the trend of the disease burden by infective endocarditis and compare with the national level.Results From 1990 to 2019,the age-standardized incidence rate(ASIR)and age-standardized YLD rate(ASYLDR)of infective endocarditis showed upward trends,while the age-standardized mortality rate(ASMR),age-standardized YLL rate(ASYLLR)and age-standardized DALY rate(ASDR)showed downward trends in Hainan.In 2019,the ASIR and ASMR of infective endocarditis were 15.14/100000 and 0.27/100000,respectively.The DALY,YLD and YLL were 762.70,22.55 and 740.15 person years,respectively,and the age standardized rates were 7.63/100000,0.23/100000 and 7.40/100000,respectively.The YLL accounted for 97.04% of DALY.In 2019,the ASDR,ASIR and ASMR of infective endocarditis were higher in men than in women.In different age groups,the incidence rate,mortality rate and DALY rate were highest in age group≥95 years.From 1990 to 2019,the ASIR of infective endocarditis was higher in Hainan compared with the national average level,but the differences in other indicators became smaller.Conclusion From 1990 to 2019,the overall disease burden by infective endocarditis showed a mitigation trend in Hainan,but the ASIR and ASYLDR showed upward trends.The ASIR might continue to increase in the future.More attention should be paid to the elderly to reduce the disease burden of disease cau

关 键 词：感染性心内膜炎 疾病负担 伤残调整寿命年 伤残损失寿命年 早死损失寿命年 

分 类 号：R211[医药卫生—中医学] R542.4