外阴硬化性苔藓的研究进展  

Research progress of the vulvar lichen sclerosus

作　　者：苏远华 肖雁冰 SU Yuan-hua;XIAO Yan-bing(Department of Gynaecology,Guizhou Aerospace Hospital,Zunyi Guizhou 563000,China;Department of Gynaecology and Obstetrics,Maternal and Child Health Hospital Affiliated to Zunyi Medical University,Zunyi Guizhou 563000,China)

机构地区：[1]贵州航天医院妇科,贵州遵义563000 [2]遵义医科大学附属妇幼保健院妇产科,贵州遵义563000

出　　处：《局解手术学杂志》2025年第4期358-362,共5页Journal of Regional Anatomy and Operative Surgery

基　　金：国家自然科学基金(81660293)。

摘　　要：外阴硬化性苔藓(LS)是一种发病机制不明的慢性炎症性皮肤黏膜疾病,可能导致外阴瘢痕形成和性功能障碍,严重影响患者的生活质量。遗传、自身免疫、感染、环境和激素等因素均可能与外阴LS的发病相关,且其临床诊断和治疗也存在着许多不确定性。因此,本文在大量查阅相关文献的基础上,对外阴LS的发病机制、诊断与评估、治疗方法、预后与管理等几个方面进行了综述。Vulvar lichen sclerosus(LS)is a chronic inflammatory skin and mucosal disease with unknown pathogenesis,which may lead to scar formation of the external genitalia and sexual dysfunction,seriously affecting the quality of life of patients.Genetic factors,autoimmune factors,infections,environment,and hormones are associated with the onset of vulvar LS,and there are also many uncertainties in its clinical diagnosis and treatment.Therefore,based on extensive literatures,this article provides a review of the pathogenesis,diagnosis and evaluation,treatment methods,prognosis and management of vulvar LS.

关 键 词：外阴硬化性苔藓 发病机制 临床诊断 治疗方法 进展 

分 类 号：R751[医药卫生—皮肤病学与性病学] R711[医药卫生—临床医学]