醒神调形针治疗气虚血瘀型脑梗死恢复期临床研究  

Clinical Study on Xingshen Tiaoxing Needle in the Treatment of Qi Deficiency and Blood Stasis TypeCerebral Infarction in the Recovery Period

作　　者：王桢 代礼霜 WANG Zhen;DAI Lishuang(Department of Preventive Medicine,Gaoming District Hospital of Traditional Chinese Medicine,Foshan City,Foshan 528500,China)

机构地区：[1]佛山市高明区中医院治未病科,广东佛山528500

出　　处：《中西医结合研究》2025年第2期85-88,共4页Research of Integrated Traditional Chinese and Western Medicine

摘　　要：目的分析醒神调形针对气虚血瘀型脑梗死恢复期患者中医证候积分、神经细胞因子及神经功能的影响。方法选择2023年1月—2024年8月本院收治的脑梗死恢复期患者93例,依据随机数字表法分为2组。对照组46例接受脑梗死恢复期常规治疗,观察组47例接受常规治疗联合醒神调形针治疗。治疗4周后,比较2组患者治疗前后中医证候积分、神经细胞因子水平,并以美国国立卫生研究院卒中量表(National Institute of Health stroke scale,NIHSS)、简化Fugl-Meyer量表(Fugl-Meyer assessment scale,FMA)评估2组患者神经功能。结果治疗后,观察组中医证候积分均显著低于对照组(P<0.05)。观察组脑源性神经生长因子(brain-derived growth factor,BDNF)、神经生长因子(nerve growth factor,NGF)水平显著高于对照组(P<0.05),神经元特异性烯醇化酶(neuron specific enolase,NSE)水平显著低于对照组(P<0.05)。观察组NIHSS评分显著低于对照组(P<0.05),FMA评分显著高于对照组(P<0.05)。结论醒神调形针治疗气虚血瘀型脑梗死恢复期可缓解患者临床症状,提高神经细胞因子水平,促进神经功能和运动功能的恢复。Objective To explore the effects of Xingshen Tiaoxing needle on the Traditional Chinese medicine(TCM)syndrome score,nerve cell factors,and neurological function of patients with qi deficiency and blood stasis type cerebral infarction in the recovery period.Methods Ninety-three patients in the recovery period of cerebral infarction admitted to our hospital from January 2023 to August 2024 were selected and divided into 2 groups according to the random number table method.Forty-six cases in the control group received conventional treatment in the recovery period of cerebral infarction,while 47 cases in the observation group received conventional treatment combined with Xingshen Tiaoxing needle.After 4 weeks of treatment,the TCM syndrome scores and levels of neuronal cytokine were compared between two groups of patients before and after treatment,and their neurological function was evaluated by the National Institute of Health stroke scale(NIHSS)and the simplified Fugl-Meyer assessment scale(FMA).Results After treatment,the TCM syndrome scores in the observation group were significantly lower than those in the control group(P<0.05).The levels of brain-derived growth factor(BDNF)and nerve growth factor(NGF)in the observation group were significantly higher than those in the control group(P<0.05),while the level of neuron specific enolase(NSE)was significantly lower than that in the control group(P<0.05).The NIHSS score of the observation group was significantly lower than that of the control group(P<0.05),and the FMA score was significantly higher than that of the control group(P<0.05).Conclusion Xingshen Tiaoxing needle could relieve the clinical symptoms of patients with qi deficiency and blood stasis type cerebral infarction in the recovery period,improve the level of nerve cytokines,and promote the recovery of nerve function and motor function.

关 键 词：脑梗死恢复期 气虚血瘀 醒神调形针 神经细胞因子 神经功能 

分 类 号：R277.7[医药卫生—中医学] R743.33