基于数据挖掘探讨田德禄教授治疗慢性萎缩性胃炎的用药规律  

Prescribing Pattern of Professor Tian Delu in Treating Chronic Atrophic Gastritis Based on Data Mining

作　　者：王文颖[1] 张雯[2] 陈维玲 赵艳[1] 熊长霞 杨思雯[3] WANG Wenying;ZHANG Wen;CHEN Weiling;ZHAO Yan;XIONG Changxia;YANG Siwen(Department of Dermatology,Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100700,China;Department of Spleen and Stomach Diseases,Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100700,China;Department of Critical Care Medicine,Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University,Beijing 100010,China)

机构地区：[1]北京中医药大学东直门医院皮肤科,北京100700 [2]北京中医药大学东直门医院脾胃病科,北京100700 [3]首都医科大学附属北京中医医院重症医学科,北京100010

出　　处：《基层中医药》2025年第3期85-91,共7页Basic Traditional Chinese Medicine

基　　金：第七批全国老中医药专家学术经验继承工作项目(国中医药人教函[2022]76号)。

摘　　要：目的 基于数据挖掘探讨田德禄教授治疗慢性萎缩性胃炎(CAG)的用药规律。方法收集2021年9月—2024年9月田德禄教授治疗CAG的医案,录入中医传承辅助平台(V2.5),并应用频次统计、关联规则和聚类分析等方法分析处方。结果 本研究共计纳入处方117首,涉及药物183味,总频次2 767次,高频药物有紫苏梗、麦芽、山楂、神曲、香附、紫苏子等;性味以温、平和辛、甘、苦为主,多归脾、胃、肺、肝经,功效以补虚、理气、清热为主;关联规则分析得到20组常用药对;聚类分析分为5个核心药组。结论 田德禄教授认为CAG病机为本虚标实,脾虚为本,气、痰、瘀为实,治疗宜清降为先,肝肺同调,调气和血,顾护胃气,清补善后。Objective To analyze the prescribing patterns of Professor Tian Delu in treating chronic atrophic gastritis (CAG) based on data mining. Methods Medical records of CAG treatment byProf. Tian from September 2021 to September 2024 were collected and input into the TCM InheritanceAuxiliary Platform (V2.5). The prescriptions were analyzed by frequency statistics, association rules,and cluster analysis. Results A total of 117 prescriptions were involved in this study, including 183kinds of drugs with a total frequency of 2 767 times. The high-frequency drugs included PerillaeCaulis, Hordei Fructus Germinatus, Crataegi Fructus, Massa Medicata Fermentata, Cyperi Rhizoma ,and Perillae Fructus . Their natures were mainly warm and neutral, with spicy, sweet, and bitteras the dominant flavors. They primarily targeted the spleen, stomach, lung, and liver meridians,tonifying deficiency, regulating Qi, and clearing heat. Twenty pairs of common drugs were obtained byassociation rule analysis, and cluster analysis identified five core drug groups. Conclusion Prof. Tianconsiders the pathogenesis of CAG as root deficiency and branch excess, with deficiency of the spleenas the root and Qi, phlegm, and blood stasis as the excess. The treatment should prioritize clearingand descending methods, addressing both the liver and lung, regulating Qi and blood, protecting thestomach Qi, and then focusing on tonifying and recovery in the later stages.

关 键 词：慢性萎缩性胃炎 数据挖掘 用药规律 田德禄 

分 类 号：R256.3[医药卫生—中医内科学]