中药活性成分抗皮肤癣菌的最新研究进展  

The latest research progress of the active ingredients of traditional Chinese medicine against dermatophyton

作　　者：兰善玉 邹宇宁 徐淼 杨青青 赵亮 陈璐颖 占萍 LAN Shanyu;ZOU Yuning;XU Miao;YANG Qingqing;ZHAO Liang;CHEN Luying;ZHAN Ping(Jiangxi University of Chinese Medicine,Nanchang 330004,China;Department of Dermatology,Seventh People's Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200137,China)

机构地区：[1]江西中医药大学,南昌330004 [2]上海中医药大学附属第七人民医院皮肤科,上海200137

出　　处：《中国真菌学杂志》2025年第1期98-103,共6页Chinese Journal of Mycology

基　　金：江西省中医药管理局重点项目(2023Z008);浦东新区高峰高原学科建设临床医学新质专科(专病)项目(2025-PWXZ-12);浦东新区中医药传承创新发展示范试点项目(YC-2023-0609)。

摘　　要：皮肤癣菌感染是皮肤科最常见的感染性疾病,传统抗皮肤癣菌病的药物种类有限,主要包括唑类和丙烯胺类。近年来出现的耐药皮肤癣菌给该病的治疗带来严峻挑战。中草药在我国具有数千年的应用历史,其中多种活性成分可有效抑制皮肤癣菌。该文综述中药活性成分对皮肤癣菌的抗菌作用和潜在机制的最新研究,并介绍了中药活性成分开发与应用的现状和发展前景。Dermatophytosis is the most common infectious disease in dermatology.The traditional anti-dermatophytosis drugs are limited,mainly including azole and acrylamide.The emergence of drug-resistant dermatophytes in recent years has brought serious challenges to the treatment of the disease.Chinese herbal medicine has been used in China for thousands of years,and many active ingredients can effectively inhibit dermatophyton.This paper reviewed the latest research on the antifungal action and potential mechanism of the active components of traditional Chinese medicine against dermatophyton,and introduced the development and application of the active components of traditional Chinese medicine.

关 键 词：中药 活性成分 皮肤癣菌 作用机制 

分 类 号：R978.5[医药卫生—药品]