暖宫汤对寒凝血淤型月经量少患者月经状况及子宫动脉血流的影响  

Effect of Nuan′gong Decoction on the Menstrual Status and Uterine Artery Blood Flow in Patients with Cold Coagulation and Blood Stasis Type Oligomenorrhea

作　　者：马红雨 朴文青 杨华 李悦[2] 曲丹 MA Hongyu;PIAO Wenqing;YANG Hua(Department of Gynecology,Qiqihar Hospital of Traditional Chinese Medicine,Heilongjiang 161000,China)

机构地区：[1]齐齐哈尔市中医医院妇科,161000 [2]黑龙江中医药大学,哈尔滨150006

出　　处：《医学研究杂志》2025年第3期85-89,共5页Journal of Medical Research

基　　金：黑龙江省中医药科研项目(ZHY2022-011)。

摘　　要：目的探讨暖宫汤治疗寒凝血淤型月经量少患者的临床疗效。方法选取120例月经量少患者,采用随机数字表法将其分为两组,即雌孕激素组和暖宫汤组,每组各60例。雌孕激素组给予雌孕激素序贯疗法进行治疗,暖宫汤组在雌孕激素组的基础上给予暖宫汤治疗。比较两组的疗效、月经状况及子宫动脉血流变化情况。结果暖宫汤组总有效率为91.67%,较雌孕激素组(76.67%)明显提升(P<0.05)。治疗后,暖宫汤组中医证候积分、中文版月经症状量表(menstrual distress questionnaire,MDQ)评分均低于雌孕激素组(P<0.05)。治疗后,暖宫汤组患者行经时间长于雌孕激素组(P<0.05),月经失血图(pictorial blood loss assessment chart,PBAC)评分高于雌激素组(P<0.05)。治疗后,暖宫汤组患者孕酮(progesterone,P)、雌二醇(estradiol,E_(2))、黄体生成素(luteinizing hormone,LH)、卵泡刺激素(follicular stimulating hormone,FSH)水平均高于雌孕激素组(P<0.05)。治疗后,暖宫汤组患者子宫动脉搏动指数(pulsitility index,PI)、阻力指数(resistance index,RI)及收缩期峰值流速/舒张期峰值流速(systolic/diastolic peak flow velocity,S/D)均低于雌孕激素组。结论对于寒凝血淤型月经量少患者,采用暖宫汤进行中医辨证治疗能够获得显著疗效,可有效延长患者行经时间,恢复月经量及性激素水平,改善子宫动脉血流参数。Objective To investigate the clinical effect of Nuan′gong decoction in the treatment of cold coagulation and blood stasis type menorrhagia.Methods A total of 120 patients with oligomenorrhea were selected and divided into two groups according to random number table method:estrogen and progesterone group and Nuan′gong decoction.The estrogen and progesterone group was treated with sequential estrogen and progesterone therapy,while the Nuan′gong decoction group was treated with Nuan′gong decoction on the top of the estrogen and progesterone group.The therapeutic effects,menstrual status,and changes in uterine artery blood flow were compared between the two groups.Results The total effective rate of the Nuan′gong decoction group was 91.67%,which was greatly higher than the 76.67%of the estrogen and progesterone group(P<0.05).After treatment,the traditional Chinese medicine syndrome score and menstrual distress questionnaire(MDQ)Chinese version score of the Nuan′gong decoction group were lower than those of the estrogen and progesterone group(P<0.05).After treatment,the duration of menstruation in the Nuan′gong decoction group was longer than that in the estrogen and progesterone group(P<0.05),and the pictorial blood loss assessment chart(PBAC)score was higher than that in the estrogen and progesterone group(P<0.05).After treatment,the levels of progesterone(P),estradiol(E_(2)),luteinizing hormone(LH),and follicle stimulating hormone(FSH)in the Nuan′gong decoction group were higher than those in the estrogen and progesterone group(P<0.05).After treatment,the uterine artery pulsatility index(PI),resistance index(BI)and systolic/diastolic peak flow velocity(S/D)in the Nuan′gong decoction group were lower than those in the estrogen and progesterone group.Conclusion For patients with cold coagulation and blood stasis type oligomenorrhea,Nuan′gong decoction for traditional Chinese medicine syndrome differentiation treatment can achieve great therapeutic effects,effectively prolong the duration of menstr

关 键 词：月经量少 寒凝血淤型 暖宫汤 月经状况 子宫动脉血流 

分 类 号：R271.111[医药卫生—中医妇科学]