丹阳市人民医院甲型流感病毒感染患儿并发肺炎的危险因素分析及预测模型构建  

Analysis of Risk Factors and Construction of a Prediction Model for Pneumonia Complicating Influenza A Virus Infection in Children in The People’s Hospital of Danyang

作　　者：徐言芳 Xu Yanfang(Department of Pediatrics,The People’s Hospital of Danyang,Danyang,Jiangsu 212300)

机构地区：[1]丹阳市人民医院儿科,江苏丹阳212300

出　　处：《科技与健康》2025年第4期157-160,共4页Technology and Health

摘　　要：探究丹阳市人民医院儿童甲型流感(甲流)病毒感染并发肺炎的危险因素并构建相应的风险预测模型。纳入2022年11月—2023年12月于医院儿科住院的甲流病毒感染患儿为研究对象(n=198),将其分为未并发肺炎的甲A组(n=130)和并发肺炎的甲B组(n=68)。分析两组患儿的一般资料、首诊症状、实验室检查结果,筛选出导致甲流病毒感染患儿并发肺炎的独立危险因素,并构建预测模型。结果显示,甲A组的发热、咳痰人数占比显著低于甲B组(P<0.05)。甲A组的CRP、LDH水平、WBC计数、IL-6、IL-34显著低于甲B组(P<0.05),PLT、各年龄段的LYM绝对值显著高于甲B组(P<0.05)。经筛选得,LYM、LDH、IL-6为影响甲流病毒感染患儿并发肺炎的独立危险因素(P<0.05)。研究发现,LYM、LDH和IL-6是甲流病毒感染患儿并发肺炎的独立危险因素,基于此构建的预测模型有较好的实用性。This study aims to explore the risk factors for pneumonia complicating influenza A virus infection in children in The People’s Hospital of Danyang and construct a corresponding risk prediction model.Children infected with influenza A virus who were hospitalized in the Department of Pediatrics of the hospital from November 2022 to December 2023 were included as the research subjects(n=198),and they were divided into group A(n=130)without pneumonia complication and group B(n=68)with pneumonia complication.The general data,initial diagnosis symptoms,and laboratory examination results of the children in the two groups were analyzed to screen out the independent risk factors for pneumonia complicating influenza A virus infection in children,and a prediction model was constructed.The results showed that the proportions of children with fever and expectoration in group A were significantly lower than those in group B(P<0.05).The levels of C-reactive protein(CRP),lactate dehydrogenase(LDH),white blood cell(WBC)count,interleukin-6(IL-6),and interleukin-34(IL-34)in group A were significantly lower than those in group B(P<0.05),while the platelet(PLT)count and the absolute values of lymphocytes(LYM)in each age group in group A were significantly higher than those in group B(P<0.05).After screening,LYM,LDH,and IL-6 were identified as independent risk factors for pneumonia complicating influenza A virus infection in children(P<0.05).The study found that LYM,LDH,and IL-6 are independent risk factors for pneumonia complicating influenza A virus infection in children,and the prediction model constructed based on them has good practicality.

关 键 词：儿童 甲流 肺炎 危险因素 预测模型 

分 类 号：R511.7[医药卫生—内科学] R563.1[医药卫生—临床医学]