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作 者:张留 刘燎原 ZHANG Liu;LIU Liaoyuan(Xi an TCM Hospital of Encephalopathy,Shaanxi Xi an 710032,China)
出 处:《安徽中医药大学学报》2025年第2期68-72,共5页Journal of Anhui University of Chinese Medicine
摘 要:目的观察接气通经法针刺联合吞咽康复训练治疗缺血性脑卒中后吞咽障碍的疗效。方法将84例缺血性脑卒中伴吞咽障碍患者随机分为观察组和对照组,每组42例。在西药治疗及吞咽康复训练基础上,对照组加用常规针刺治疗,观察组在对照组疗法基础上针刺廉泉、风府穴,行接气通经针刺手法。两组均每日针刺1次,每周治疗5 d,疗程4周。采用标准吞咽功能评定量表(standardized swallowing assessment,SSA)、吞咽相关生命质量量表(swallowing-related quality of life questionnaire,SWAL-QOL)评价患者吞咽功能和生活质量,并检测血清中脑源性神经营养因子(brain-derived neurotrophic factor,BDNF)、胶质细胞源性神经营养因子(glial cell line-derived neurotrophic factor,GDNF)水平。结果与治疗前比较,治疗后两组患者SSA评分均显著降低(P<0.05),SWAL-QOL评分及血清BDNF、GDNF水平均显著升高(P<0.05);观察组患者SWAL-QOL评分及血清BDNF、GDNF水平升高程度均显著大于对照组(P<0.05)。结论在常规针刺联合西药治疗、吞咽康复训练基础上,接气通经法针刺可显著改善缺血性脑卒中后吞咽障碍患者吞咽功能,提高患者生活质量,其机制可能与升高患者血清BDNF、GDNF水平有关。Objective To investigate the clinical effect of Qi-monitoring and meridian-connecting acupuncture combined with swallowing rehabilitation training in the treatment of dysphagia after ischemic stroke.Methods A total of 84 patients with ischemic stroke and dysphagia were randomly divided into observation group and control group,with 42 patients in each group.The patients in the control group were given Western medicine treatment,swallowing rehabilitation training,and conventional acupuncture,and those in the observation group were given Qi-monitoring and meridian-connecting acupuncture at Lianquan and Fengfu points in addition to the treatment in the control group.Both groups were given acupuncture once a day for 5 days a week,with a course of treatment of 4 weeks.Standardized Swallowing Assessment(SSA)and swallowing-related quality of life questionnaire(SWAL-QOL)were used to evaluate swallowing function and quality of life,and the serum levels of brain-derived neurotrophic factor(BDNF)and glial cell line-derived neurotrophic factor(GDNF)were measured.Results After treatment,both groups had a significant reduction in SSA score(P<0.05)and significant increases in SWAL-QOL score and the serum levels of BDNF and GDNF(P<0.05),and compared with the control group,the observation group had significantly greater increases in SWAL-QOL score and the serum levels of BDNF and GDNF(P<0.05).Conclusion In addition to conventional acupuncture combined with Western medicine treatment and swallowing rehabilitation training,Qi-monitoring and meridian-connecting acupuncture can significantly improve the swallowing function and quality of life of patients with dysphagia after ischemic stroke,possibly by increasing the serum levels of BDNF and GDNF in patients.
关 键 词:接气通经法针刺 缺血性脑卒中 吞咽障碍 脑源性神经营养因子 胶质细胞源性神经营养因子
分 类 号:R246.6[医药卫生—针灸推拿学]
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