胆道闭锁患儿脂溶性维生素缺乏及防治的研究进展  

Research progress of fat-soluble vitamin deficiency and its prevention in children with biliary atresia

作　　者：计琪 杨千慧 张焱然 刘邵文 詹江华[1] Ji Qi;Yang Qianhui;Zhang Yanran;Liu Shaowen;Zhan Jianghua(Department of General Surgery,Tianjin Children’s Hospital(Tianjin University Children’s Hospital),Tianjin 300134,China)

机构地区：[1]天津市儿童医院(天津大学儿童医院)普外科,天津300134

出　　处：《中华肝胆外科杂志》2025年第3期236-240,共5页Chinese Journal of Hepatobiliary Surgery

基　　金：天津市应用基础研究项目(22JCZDJC00290);天津市医学重点学科(专科)建设项目(TJYXZDXK-04OA)。

摘　　要：胆道闭锁是波及肝内外胆管的闭塞性病变,目前临床上胆道闭锁常用的治疗方式是肝门空肠吻合术(Kasai手术),术后辅以糖皮质激素、抗生素等。然而临床上胆道闭锁患儿出现脂溶性维生素缺乏的现象较为普遍,导致生长发育迟缓以及营养不良,进一步影响患儿治疗和预后等。本文总结了胆道闭锁患儿脂溶性维生素缺乏的病因、临床表现以及防治的研究现状。Biliary atresia is a progressive disease involving the intrahepatic and extrahepatic bile ducts.At present,the widely used treatment strategy is portojejunostomy(Kasai procedure).However,fat-soluble vitamin deficiency is common in children with biliary atresia,leading to growth retardation and malnutrition,which further affects the therapeutic effect prognosis of children.This article reviews the etiology,performance,prevention and treatment of fat-soluble vitamins deficiency in children with biliary atresia.

关 键 词：胆道闭锁 营养不良 病因 脂溶性维生素 治疗 

分 类 号：R726.5[医药卫生—儿科]