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作 者:章毅 季晨 王幸畑 ZHANG Yi;JI Chen;WANG Xingtian(Department of Urology,the People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine,Fuzhou Fujian 350004,China)
机构地区:[1]福建中医药大学附属人民医院泌尿外科,福建福州350004
出 处:《中国卫生标准管理》2025年第5期164-167,共4页China Health Standard Management
基 金:福建中医药大学2021年度校管临床专项课题(XB2021006)。
摘 要:目的探讨排石经验方联合西药及自拟排石操综合治疗输尿管结石的临床疗效。方法选取2021年7月—2023年7月福建中医药大学附属人民医院泌尿外科收治的60例输尿管结石患者为研究对象。根据不同治疗药物分为对照组和试验组,每组30例,对照组予以排石颗粒联合盐酸坦索罗辛缓释胶囊、呋塞米片治疗,试验组予以排石经验方联合盐酸坦索罗辛缓释胶囊、呋塞米片治疗,所有患者每日至少1次在短时间内饮水0.5~1 L后进行自拟排石操运动。比较2组14、28 d的排石率及不良反应发生率。结果试验组治疗后14、28 d的排石率分别为86.67%、93.33%,高于对照组的63.33%、70.00%,差异均有统计学意义(P<0.05)。2组均无药物过敏反应发生,试验组发生胃脘痛1例,腹泻1例,不良反应发生率为6.67%,对照组发生胃脘痛2例,腹泻1例,不良反应发生率为10.00%,但2组不良反应发生率比较差异无统计学意义(P>0.05)。结论排石经验方联合西药及自拟排石操综合治疗输尿管结石,能够有效促进输尿管结石自然排出,临床效果好,可扩大样本量进行深入研究。Objective To explore the clinical efficacy of Paishi experiential prescription combined with Western medicine and self-designed discharging stone exercise in the comprehensive treatment of ureteral calculi.Methods From July 2021 to July 2023,60 patients with ureteral calculi admitted to the department of urology at the People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine were selected as the research subjects.They were divided into a control group and an experimental group according to different treatment medications, with 30 cases in each group. The control group was treated with Paishi granules in combination with tamsulosin hydrochloride sustained-release capsules and furosemide tablets, while the experimental group was treated with Paishi experiential prescription in combination with tamsulosin hydrochloride sustained-release capsules and furosemide tablets. All patients were required to drink 0.5-1 L of water in a short period at least once a day and then perform a self- designed discharging stone exercise. The stone-expelling rates and the incidence of adverse reactions at 14 and 28 days were compared between the two groups. Results After treatment, the stone expulsion rates of the experimental group at 14 and 28 days were 86.67% and 93.33%, respectively, which were higher than those of the control group (63.33% and 70.00%), with statistically significant differences (P < 0.05). No drug allergic reactions occurred in either group. In the experimental group, 1 case of epigastric pain and 1 case of diarrhea, with a total adverse reaction incidence rate of 6.67%. In the control group, 2 cases of epigastric pain and 1 case of diarrhea, with a total adverse reaction incidence rate of 10.00%. However, there was no statistically significant difference in the incidence of adverse reactions between the two groups (P > 0.05). Conclusion The integrated treatment of ureteral calculi using Paishi experiential prescription in combination with Western medicine and self-designed discharging sto
关 键 词:输尿管结石 排石经验方 中西医结合 α1肾上腺素能受体阻断剂 肾俞穴 水道穴 疗效
分 类 号:R243[医药卫生—中医临床基础]
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