新型冠状病毒感染对双腔起搏器植入患者新发亚临床心房颤动的影响  

The impact of novel coronavirus infection on new-onset subclinical atrial fibrillation in patients with dual-chamber pacemaker implantation

作　　者：殷荣荣 韩智红[1] 赵华[1] 吕力知 李刚[2] 任学军[1] Yin Rongrong;Han Zhihong;Zhao Hua;Lyu Lizhi;Li Gang;Ren Xuejun(The Cardiac Pacing and CIED Center,Beijing Anzhen Hospital,Capital Medical University,Beijing 100029,China;Pediatric Cardiac Center,Beijing Anzhen Hospital,Capital Medical University,Beijing 100029,China)

机构地区：[1]首都医科大学附属北京安贞医院心脏起搏与CIED中心,北京100029 [2]首都医科大学附属北京安贞医院小儿心脏中心,北京100029

出　　处：《中国医药》2025年第4期491-494,共4页China Medicine

基　　金：国家科技重大专项青年人才培育计划(2023ZD0514400)。

摘　　要：目的探讨新型冠状病毒感染(COVID-19)对双腔起搏器植入患者新发亚临床心房颤动的影响。方法回顾性分析2016年1月至2023年6月在首都医科大学附属北京安贞医院首次植入永久双腔起搏器的420例患者的临床资料。将患者根据是否合并COVID-19分为感染组和未感染组。比较2组随访资料和亚临床心房颤动发生情况。采用多因素Logistic回归模型分析影响亚临床心房颤动发生的独立危险因素。结果420例患者中共395例完成24.0(6.0,54.0)个月的随访,其中感染组323例,未感染组72例。随访过程中有3例患者死亡,其中1例肾衰竭、另外2例原因不详,死亡患者均合并COVID-19。感染组亚临床心房颤动发生率明显高于未感染组[16.7%(54/323)比6.9%(5/72)](P=0.035)。多因素Logistic回归分析结果显示,合并COVID-19、大于2 s长RR间期、左心房内径增大是患者发生亚临床心房颤动的独立危险因素(均P<0.05)。结论合并COVID-19、大于2 s长RR间期、左心房内径增大均是植入永久双腔起搏器患者发生亚临床心房颤动的独立危险因素。Objective To investigate the impact of novel coronavirus infection(COVID-19)on new-onset subclinical atrial fibrillation in patients with dual-chamber pacemaker implantation.Methods The clinical data of 420 patients who were implanted with permanent dual-chamber pacemaker for the first time in Beijing Anzhen Hospital,Capital Medical University from January 2016 to June 2023 were retrospectively analyzed.The patients were divided into infection group and non-infection group according to whether they were complicated with COVID-19.The follow-up data and the incidence of subclinical atrial fibrillation were compared between the two groups.Multivariate Logistic regression model was used to analyze the independent risk factors for subclinical atrial fibrillation.Results A total of 395 of 420 patients completed 24.0(6.0,54.0)months of follow-up,including 323 patients in the infection group and 72 patients in the non-infection group.Three patients died during the follow-up,including one with renal failure and the other two with unknown causes,all of whom were complicated with COVID-19.The incidence of subclinical atrial fibrillation in the infection group was significantly higher than that in the non-infection group[16.7%(54/323)vs 6.9%(5/72)](P=0.035).Multivariate Logistic regression analysis showed that COVID-19,longer RR interval(>2 s)and enlarged left atrial diameter were independent risk factors for subclinical atrial fibrillation(all P<0.05).Conclusion COVID-19,longer RR interval(>2 s),and enlarged left atrial diameter are independent risk factors for subclinical atrial fibrillation in patients with permanent dual-chamber pacemaker implantation.

关 键 词：亚临床心房颤动 新型冠状病毒感染 双腔起搏器 

分 类 号：R541.7[医药卫生—心血管疾病]